STRINGSTRING
ece2b ece2b Edn3 Edn3 msx1a msx1a nkx3-2 nkx3-2 gsc gsc furina furina mef2ca mef2ca dlx6a dlx6a furinb furinb edn1 edn1 ek1 ek1 ece1 ece1 edn3b edn3b ednrab ednrab wnt5b wnt5b ednraa ednraa dlx2b dlx2b gnaq gnaq epha3 epha3 hand2 hand2 hoxa2b hoxa2b epha4b epha4b twist1a twist1a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ece2bEndothelin-converting enzyme 2b. (765 aa)
Edn3END domain-containing protein. (102 aa)
msx1aMuscle segment homeobox 1a. (233 aa)
nkx3-2Bagpipe homeobox transcription factor Bapx1. (245 aa)
gscHomeobox protein goosecoid. (240 aa)
furinaFurin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (806 aa)
mef2caMyocyte enhancer factor 2ca. (465 aa)
dlx6aHomeobox protein Dlx6a. (247 aa)
furinbFurin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (823 aa)
edn1Endothelin 1. (188 aa)
ek1Ephrin type-A receptor 3; Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially efna5. Upon activation by efna5 regulates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in ca [...] (981 aa)
ece1Endothelin-converting enzyme 1. (752 aa)
edn3bEndothelin 3b. (153 aa)
ednrabEndothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (408 aa)
wnt5bProtein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. Required during embryogenesis for extension of the primary anterior-posterior axis. (363 aa)
ednraaEndothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (422 aa)
dlx2bHomeobox protein Dlx2b. (276 aa)
gnaqGuanine nucleotide-binding protein (G protein), q polypeptide. (359 aa)
epha3Ephrin type-A receptor 3. (963 aa)
hand2Heart- and neural crest derivatives-expressed protein 2; Essential for myocardial and pectoral fin differentiation, patterning and morphogenesis. (205 aa)
hoxa2bHomeobox protein Hox-A2b; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (363 aa)
epha4bEph receptor A4b. (976 aa)
twist1aTwist family bHLH transcription factor 1a. (171 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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