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sema3e | Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; Belongs to the semaphorin family. (768 aa) | ||||
chrd | Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity); Belongs to the chordin family. (940 aa) | ||||
pax3a | Transcription factor PAX3. (509 aa) | ||||
fgf8a | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. (210 aa) | ||||
gbx2 | Gastrulation brain homeo box 2. (342 aa) | ||||
cdh2 | Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion (By similarity). Cadherins contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development. Required for normal neural tube morphogenesis. Required to allow mid- and hindbrain neurons to reach and maintain their appropriate positions within the neural tube by restricting neuronal motility within the embryonic mid- and hindbrain. (893 aa) | ||||
msx1a | Muscle segment homeobox 1a. (233 aa) | ||||
irf6 | Interferon regulatory factor 6. (492 aa) | ||||
ctnnb1 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] (789 aa) | ||||
hdac4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1023 aa) | ||||
cdh1 | Cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. (877 aa) | ||||
foxe1 | Forkhead box E1. (375 aa) | ||||
tbx22 | T-box transcription factor 22. (334 aa) | ||||
tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. (369 aa) | ||||
chd7 | Chromodomain helicase DNA-binding protein 7. (3140 aa) | ||||
snai1a | Snail family zinc finger 1a. (260 aa) | ||||
zic1 | ZIC family member 1 (Odd-paired homolog, Drosophila). (442 aa) | ||||
sox10 | HMG-box transcription factor Sox10. (485 aa) | ||||
hdac5 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1128 aa) | ||||
edn1 | Endothelin 1. (188 aa) | ||||
bmp4 | Bone morphogenetic protein 4. (400 aa) | ||||
snai1b | Snail family zinc finger 1b. (256 aa) | ||||
acta1b | Actin alpha 1, skeletal muscle b. (377 aa) | ||||
wnt9b | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |