STRINGSTRING
cfl2 cfl2 cfl1 cfl1 acta1b acta1b bcl2a bcl2a cfl1l cfl1l bace1 bace1 psen1 psen1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cfl2Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
cfl1Muscle cofilin 2; Belongs to the actin-binding proteins ADF family. (165 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
bcl2aB-cell leukemia/lymphoma 2. (228 aa)
cfl1lCofilin 1 (non-muscle),-like; Belongs to the actin-binding proteins ADF family. (163 aa)
bace1Beta-secretase 1; Belongs to the peptidase A1 family. (221 aa)
psen1Presenilin-1; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins (By similarity); Belongs to the peptidase A22A family. (456 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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