STRINGSTRING
cdh1 cdh1 cxcl12a cxcl12a cxcr4b cxcr4b ackr3b ackr3b nanos3 nanos3 pax6a pax6a nanos1 nanos1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdh1Cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. (877 aa)
cxcl12aChemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1); Belongs to the intercrine alpha (chemokine CxC) family. (99 aa)
cxcr4bChemokine (C-X-C motif), receptor 4b; Belongs to the G-protein coupled receptor 1 family. (353 aa)
ackr3bAtypical chemokine receptor 3b; Belongs to the G-protein coupled receptor 1 family. (362 aa)
nanos3Nanos homolog 3; Belongs to the nanos family. (159 aa)
pax6aPaired box protein Pax-6; Transcription factor expressed in spatially restricted regions of the neural tube during embryonic development; Belongs to the paired homeobox family. (451 aa)
nanos1Nanos homolog 1; Acts as a translational repressor. Can mediate repression affecting different steps in the translation process: cap-driven, IRES- driven, polyadenylated RNAs or nonpolyadenylated RNAs (By similarity). Essential for the development of primordial germ cells (PGCs) by ensuring their proper migration and survival. (228 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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