node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
atoh1a | notch1a | ENSDARP00000105581 | ENSDARP00000137942 | Atonal bHLH transcription factor 1a. | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | 0.833 |
atoh1a | pax2a | ENSDARP00000105581 | ENSDARP00000071466 | Atonal bHLH transcription factor 1a. | Paired box protein Pax-2a; Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation. | 0.744 |
cebpg | cux1b | ENSDARP00000052364 | ENSDARP00000063328 | CCAAT/enhancer binding protein (C/EBP), gamma. | Cut-like homeobox 1b. | 0.443 |
cux1b | cebpg | ENSDARP00000063328 | ENSDARP00000052364 | Cut-like homeobox 1b. | CCAAT/enhancer binding protein (C/EBP), gamma. | 0.443 |
ins | insb | ENSDARP00000051221 | ENSDARP00000115146 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.905 |
ins | notch1a | ENSDARP00000051221 | ENSDARP00000137942 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | 0.748 |
ins | prkacaa | ENSDARP00000051221 | ENSDARP00000135348 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. | 0.690 |
ins | prkacab | ENSDARP00000051221 | ENSDARP00000002825 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. | 0.690 |
ins | prkacba | ENSDARP00000051221 | ENSDARP00000023805 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Protein kinase, cAMP-dependent, catalytic, beta a; Belongs to the protein kinase superfamily. | 0.690 |
ins | prkacbb | ENSDARP00000051221 | ENSDARP00000076580 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. | 0.691 |
ins | tgfb1a | ENSDARP00000051221 | ENSDARP00000060838 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.604 |
ins | tgfb1b | ENSDARP00000051221 | ENSDARP00000122056 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.604 |
ins | tgfb3 | ENSDARP00000051221 | ENSDARP00000025519 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.576 |
insb | ins | ENSDARP00000115146 | ENSDARP00000051221 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.905 |
insb | notch1a | ENSDARP00000115146 | ENSDARP00000137942 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | 0.748 |
insb | prkacaa | ENSDARP00000115146 | ENSDARP00000135348 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. | 0.689 |
insb | prkacab | ENSDARP00000115146 | ENSDARP00000002825 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. | 0.689 |
insb | prkacba | ENSDARP00000115146 | ENSDARP00000023805 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Protein kinase, cAMP-dependent, catalytic, beta a; Belongs to the protein kinase superfamily. | 0.689 |
insb | prkacbb | ENSDARP00000115146 | ENSDARP00000076580 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. | 0.691 |
insb | tgfb1a | ENSDARP00000115146 | ENSDARP00000060838 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.589 |