STRINGSTRING
pak1 pak1 cfl1l cfl1l cfl2 cfl2 rho rho pak4 pak4 cfl1 cfl1 pfn2l pfn2l acta1b acta1b limk2 limk2 cd2ap cd2ap pfn2 pfn2 rac1a rac1a pfn1 pfn1 TESK1 TESK1 rock2a rock2a myh9a myh9a X1WCU6_DANRE X1WCU6_DANRE cdc42 cdc42 prkd1 prkd1 RAC1 RAC1 limk1a limk1a pak2a pak2a prkd4 prkd4 rock1 rock1 prkd3 prkd3 actn4 actn4 prkd2 prkd2 inf2 inf2 nphs1 nphs1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pak1Non-specific serine/threonine protein kinase. (587 aa)
cfl1lCofilin 1 (non-muscle),-like; Belongs to the actin-binding proteins ADF family. (163 aa)
cfl2Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
rhoRhodopsin; Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity). (354 aa)
pak4Non-specific serine/threonine protein kinase. (664 aa)
cfl1Muscle cofilin 2; Belongs to the actin-binding proteins ADF family. (165 aa)
pfn2lProfilin; Belongs to the profilin family. (139 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
limk2LIM domain kinase 2. (651 aa)
cd2apCD2-associated protein. (657 aa)
pfn2Profilin; Belongs to the profilin family. (140 aa)
rac1aRas-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (192 aa)
pfn1Profilin; Belongs to the profilin family. (141 aa)
TESK1Si:ch211-113e8.3. (657 aa)
rock2aRho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1375 aa)
myh9aMyosin, heavy chain 9a, non-muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1964 aa)
X1WCU6_DANREProfilin; Belongs to the profilin family. (127 aa)
cdc42Cell division cycle 42. (191 aa)
prkd1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (886 aa)
RAC1Rac family small GTPase 1. (166 aa)
limk1aLIM domain kinase 1a. (648 aa)
pak2aNon-specific serine/threonine protein kinase. (518 aa)
prkd4Zgc:175248 protein. (660 aa)
rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1359 aa)
prkd3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (891 aa)
actn4Actinin, alpha 4. (923 aa)
prkd2Protein kinase D2. (562 aa)
inf2GBD/FH3 domain-containing protein. (238 aa)
nphs1NPHS1 adhesion molecule, nephrin. (1287 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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