STRINGSTRING
gapdh gapdh acta1b acta1b gapdhs gapdhs fermt2 fermt2 ryr1b ryr1b celf1 celf1 grin1b grin1b mylz3 mylz3 celf3a celf3a cacng1a cacng1a eif2ak2 eif2ak2 tnnt2a tnnt2a actc1b actc1b celf2 celf2 ryr1a ryr1a fermt1 fermt1 mbnl3 mbnl3 cnbpb cnbpb tnnt3a tnnt3a grin1a grin1a mbnl1 mbnl1 sesn3 sesn3 mylpfa mylpfa cnbpa cnbpa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gapdhGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] (333 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
gapdhsGlyceraldehyde-3-phosphate dehydrogenase 2; Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. (335 aa)
fermt2Fermitin family homolog 2; Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading; this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and ce [...] (684 aa)
ryr1bRyanodine receptor 1b (skeletal). (5078 aa)
celf1CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. May be involved in mRNA translation activation and stability (By similarity). Involved in the regulation of muscle-specific splicing of alpha actinin pre-mRNAs via the binding to the UR-repeat element (URE) at the branch point of the non-muscle (NM) exon; Belongs to the CELF/BRUNOL family. (534 aa)
grin1bGlutamate receptor, ionotropic, N-methyl D-aspartate 1b. (937 aa)
mylz3Fast skeletal muscle myosin light polypeptide 3. (151 aa)
celf3aCUGBP Elav-like family member 3; RNA-binding protein that may be involved in the regulation of pre-mRNA alternative splicing; Belongs to the CELF/BRUNOL family. (452 aa)
cacng1aVoltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (225 aa)
eif2ak2Eukaryotic translation initiation factor 2-alpha kinase 2. (682 aa)
tnnt2aTroponin T type 2a (cardiac). (282 aa)
actc1bActin, alpha 1, skeletal muscle. (377 aa)
celf2CUGBP Elav-like family member 2; RNA-binding protein implicated in the regulation of several post-transcriptional events. May be involved in pre-mRNA alternative splicing, mRNA translation repression and stability (By similarity). (493 aa)
ryr1aRyanodine receptor 1a (skeletal). (5062 aa)
fermt1Fermitin family member 1. (661 aa)
mbnl3Muscleblind-like-splicing regulator 3. (388 aa)
cnbpbCCHC-type zinc finger, nucleic acid-binding protein b. (161 aa)
tnnt3aTroponin T type 3a (skeletal, fast). (230 aa)
grin1aGlutamate receptor, ionotropic, N-methyl D-aspartate 1a. (901 aa)
mbnl1Muscleblind-like-splicing regulator 1. (424 aa)
sesn3Sestrin 3. (466 aa)
mylpfaMyosin light chain, phosphorylatable, fast skeletal muscle a. (169 aa)
cnbpaCCHC-type zinc finger, nucleic acid-binding protein a. (163 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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