STRINGSTRING
mylpfa mylpfa pou5f3 pou5f3 cxcr4b cxcr4b klf17 klf17 fgf24 fgf24 myf6 myf6 fabp2 fabp2 fgf8a fgf8a myog myog dmd dmd myod1 myod1 pax7a pax7a sgcd sgcd tert tert myf5 myf5 mtor mtor myca myca klf4 klf4 ptprc ptprc sox2 sox2 hist1h2a3 hist1h2a3 gata2a gata2a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mylpfaMyosin light chain, phosphorylatable, fast skeletal muscle a. (169 aa)
pou5f3POU domain, class 5, transcription factor 1; Involved in early development of embryos, especially in the process of gastrulation. May play an important role in establishing and specifying rhombomeric segments. Seems to be required to maintain the cells in a highly undifferentiated state. In contrast to POU2, T-POU2 lacks DNA-binding activity because of its incomplete pou domain structure. Overexpression of POU2 does not have any effect on development, whereas overexpression of t-POU2 causes developmental retardation or arrest before gastrulation; Belongs to the POU transcription factor [...] (472 aa)
cxcr4bChemokine (C-X-C motif), receptor 4b; Belongs to the G-protein coupled receptor 1 family. (353 aa)
klf17Kruppel-like factor 17. (409 aa)
fgf24Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
myf6Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). (239 aa)
fabp2Fatty acid-binding protein 2, intestinal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
fgf8aFibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. (210 aa)
myogMyogenin. (256 aa)
dmdDystrophin. (594 aa)
myod1Myoblast determination protein 1 homolog; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. (275 aa)
pax7aTranscription factor PAX7C. (507 aa)
sgcdSarcoglycan, delta (dystrophin-associated glycoprotein). (292 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1098 aa)
myf5Myogenic factor. (237 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2563 aa)
mycaTranscriptional regulator Myc-A; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (409 aa)
klf4Kruppel-like factor 4. (340 aa)
ptprcProtein tyrosine phosphatase receptor type C. (1130 aa)
sox2Transcription factor Sox-2; Transcriptional activator. May function as a switch in neuronal development (By similarity). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). (315 aa)
hist1h2a3Histone H2A; Belongs to the histone H2A family. (128 aa)
gata2aGATA-binding protein 2a. (456 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (26%) [HD]