STRINGSTRING
scarb1 scarb1 myd88 myd88 mapk14a mapk14a mpx mpx ncf1 ncf1 tlr2 tlr2 acta1b acta1b mmp9 mmp9 jun jun saa saa ctrl ctrl il10 il10 nfkbiaa nfkbiaa tlr18 tlr18 rela rela
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
scarb1Scavenger receptor class B, member 1; Belongs to the CD36 family. (496 aa)
myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. (284 aa)
mapk14aMitogen-activated protein kinase 14A; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Mapk14a is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are [...] (361 aa)
mpxMyeloid-specific peroxidase. (893 aa)
ncf1Neutrophil cytosolic factor 1. (410 aa)
tlr2Toll-like receptor 2. (788 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
mmp9Matrix metallopeptidase 9. (680 aa)
junJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (308 aa)
saaSerum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (121 aa)
ctrlChymotrypsin-like; Belongs to the peptidase S1 family. (261 aa)
il10Interleukin-10. (180 aa)
nfkbiaaNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (310 aa)
tlr18Toll-like receptor 18. (854 aa)
relaV-rel avian reticuloendotheliosis viral oncogene homolog A. (455 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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