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gata6 | GATA-binding protein 6. (501 aa) | ||||
nkx2.4b | NK2 homeobox 1a. (307 aa) | ||||
ptch2 | Protein patched homolog 1; Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity). Belongs to the patched family. (1442 aa) | ||||
wnt5a | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa) | ||||
foxj1a | Forkhead box protein J1-A; Key transcription factor required for motile ciliogenesis. Activates genes essential for motile cilia formation and function. Its activity is sufficient for ectopic development of cilia that resemble motile cilia. (458 aa) | ||||
wnt5b | Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. Required during embryogenesis for extension of the primary anterior-posterior axis. (363 aa) | ||||
ihha | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (413 aa) | ||||
ihhb | Indian hedgehog B protein C-product; Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning and muscle pioneer differentiation. (412 aa) | ||||
wnt3a | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) | ||||
sox2 | Transcription factor Sox-2; Transcriptional activator. May function as a switch in neuronal development (By similarity). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). (315 aa) | ||||
ift80 | Intraflagellar transport 80 homolog (Chlamydomonas). (777 aa) | ||||
ENSDARP00000125042 | Patched 1. (120 aa) | ||||
gli2a | GLI family zinc finger 2a. (1439 aa) | ||||
smo | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (822 aa) | ||||
ptch1 | Protein patched homolog 1. (1475 aa) | ||||
fgf10a | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa) | ||||
nkx2.1 | NK2 homeobox 1b. (346 aa) | ||||
gli1 | GLI family zinc finger 1. (1404 aa) | ||||
shhb | Tiggy-winkle hedgehog protein C-product; Intercellular signal essential for a variety of patterning events during development. Involved in dorso-ventral patterning of the brain and in early patterning of the developing eyes. (416 aa) | ||||
shha | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). (418 aa) |