STRINGSTRING
rhoab rhoab tgfb3 tgfb3 itga5 itga5 ptk2ab ptk2ab twist1a twist1a snai2 snai2 acta1b acta1b plaub plaub zeb2a zeb2a cdh1 cdh1 tmprss2 tmprss2 mst1 mst1 tmprss4a tmprss4a corin corin egfra egfra tgfb1b tgfb1b plat plat hcls1 hcls1 itga2.2 itga2.2 LOC100334116 LOC100334116 tgfb5 tgfb5 stat3 stat3 hgfa hgfa tm4sf5 tm4sf5 egf egf tgfb1a tgfb1a cdh2 cdh2 cttn cttn tjp1a tjp1a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rhoabRho-related GTP-binding protein RhoA-B; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. (193 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
itga5Integrin, alpha 5 (fibronectin receptor, alpha polypeptide); Belongs to the integrin alpha chain family. (1053 aa)
ptk2abProtein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1050 aa)
twist1aTwist family bHLH transcription factor 1a. (171 aa)
snai2Snail homolog 2 (Drosophila). (257 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
plaubUrokinase-type plasminogen activator b. (432 aa)
zeb2aZinc finger E-box-binding homeobox 2a. (1242 aa)
cdh1Cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. (877 aa)
tmprss2Transmembrane serine protease 2; Belongs to the peptidase S1 family. (487 aa)
mst1Macrophage stimulating 1 (Hepatocyte growth factor-like); Belongs to the peptidase S1 family. Plasminogen subfamily. (709 aa)
tmprss4aTransmembrane serine protease 4a; Belongs to the peptidase S1 family. (430 aa)
corinCorin, serine peptidase. (833 aa)
egfraEpidermal growth factor receptor precursor. (625 aa)
tgfb1bTransforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
platPlasminogen activator; Belongs to the peptidase S1 family. (578 aa)
hcls1Hematopoietic cell-specific Lyn substrate 1. (548 aa)
itga2.2Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2; Belongs to the integrin alpha chain family. (1197 aa)
LOC100334116Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (685 aa)
tgfb5Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
stat3Signal transducer and activator of transcription. (806 aa)
hgfaHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (699 aa)
tm4sf5Transmembrane 4 L six family member 5. (201 aa)
egfEpidermal growth factor. (1114 aa)
tgfb1aTransforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
cdh2Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion (By similarity). Cadherins contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development. Required for normal neural tube morphogenesis. Required to allow mid- and hindbrain neurons to reach and maintain their appropriate positions within the neural tube by restricting neuronal motility within the embryonic mid- and hindbrain. (893 aa)
cttnCortactin. (536 aa)
tjp1aTight junction protein 1a; Belongs to the MAGUK family. (1689 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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