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shha | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). (418 aa) | ||||
smo | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (822 aa) | ||||
ptch1 | Protein patched homolog 1. (1475 aa) | ||||
chrd | Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity); Belongs to the chordin family. (940 aa) | ||||
mnx1 | Motor neuron and pancreas homeobox 1. (311 aa) | ||||
tll1 | Dorsal-ventral patterning tolloid-like protein 1; Required for patterning ventral tissues of the tail. May increase bone morphogenetic protein (BMP) activity at the end of gastrulation by proteolytic cleavage of chordin and release of BMP from inactive complexes. (1022 aa) | ||||
gli3 | GLI family zinc finger 3. (1553 aa) | ||||
egf | Epidermal growth factor. (1114 aa) | ||||
id3 | Inhibitor of DNA binding 3. (116 aa) | ||||
ptch2 | Protein patched homolog 1; Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity). Belongs to the patched family. (1442 aa) | ||||
hhipl2 | HHIP-like 2. (877 aa) | ||||
hhip | Hedgehog-interacting protein. (693 aa) | ||||
ar | Androgen receptor. (868 aa) | ||||
myca | Transcriptional regulator Myc-A; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (409 aa) | ||||
ENSDARP00000125042 | Patched 1. (120 aa) | ||||
szl | Szl protein. (282 aa) | ||||
pax7a | Transcription factor PAX7C. (507 aa) |