node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DYNC2H1 | arl13b | ENSDARP00000152917 | ENSDARP00000092960 | Dynein cytoplasmic 2 heavy chain 1. | ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic intern [...] | 0.562 |
DYNC2H1 | cc2d2a | ENSDARP00000152917 | ENSDARP00000150494 | Dynein cytoplasmic 2 heavy chain 1. | Coiled-coil and C2 domain-containing 2A. | 0.531 |
DYNC2H1 | cep290 | ENSDARP00000152917 | ENSDARP00000124972 | Dynein cytoplasmic 2 heavy chain 1. | Centrosomal protein of 290 kDa; Involved in early and late steps in cilia formation. May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs). In the ciliary transition zone is part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. Involved in regulation of the BBSome complex integrity and in ciliary targeting of selected BBSome cargos. Required for the correct localization of ciliary and photot [...] | 0.672 |
DYNC2H1 | ift88 | ENSDARP00000152917 | ENSDARP00000034047 | Dynein cytoplasmic 2 heavy chain 1. | Intraflagellar transport 88 homolog. | 0.918 |
DYNC2H1 | wdr35 | ENSDARP00000152917 | ENSDARP00000091436 | Dynein cytoplasmic 2 heavy chain 1. | WD repeat-containing protein 35. | 0.881 |
acta1b | arl13b | ENSDARP00000058628 | ENSDARP00000092960 | Actin alpha 1, skeletal muscle b. | ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic intern [...] | 0.483 |
acta1b | cdh23 | ENSDARP00000058628 | ENSDARP00000026525 | Actin alpha 1, skeletal muscle b. | Cadherin-related 23. | 0.687 |
acta1b | cep290 | ENSDARP00000058628 | ENSDARP00000124972 | Actin alpha 1, skeletal muscle b. | Centrosomal protein of 290 kDa; Involved in early and late steps in cilia formation. May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs). In the ciliary transition zone is part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. Involved in regulation of the BBSome complex integrity and in ciliary targeting of selected BBSome cargos. Required for the correct localization of ciliary and photot [...] | 0.418 |
acta1b | grna | ENSDARP00000058628 | ENSDARP00000113859 | Actin alpha 1, skeletal muscle b. | Granulin a. | 0.680 |
acta1b | ift88 | ENSDARP00000058628 | ENSDARP00000034047 | Actin alpha 1, skeletal muscle b. | Intraflagellar transport 88 homolog. | 0.629 |
acta1b | mut | ENSDARP00000058628 | ENSDARP00000079877 | Actin alpha 1, skeletal muscle b. | Methylmalonyl CoA mutase. | 0.449 |
acta1b | pcdh15a | ENSDARP00000058628 | ENSDARP00000130788 | Actin alpha 1, skeletal muscle b. | Protocadherin-related 15a. | 0.596 |
acta1b | pcdh15b | ENSDARP00000058628 | ENSDARP00000141906 | Actin alpha 1, skeletal muscle b. | Protocadherin-related 15b. | 0.588 |
acta1b | pvalb7 | ENSDARP00000058628 | ENSDARP00000122628 | Actin alpha 1, skeletal muscle b. | Parvalbumin-7; In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions (By similarity). | 0.574 |
acta1b | ush1c | ENSDARP00000058628 | ENSDARP00000104974 | Actin alpha 1, skeletal muscle b. | Usher syndrome 1C (Autosomal recessive, severe). | 0.596 |
alms1 | arl13b | ENSDARP00000098408 | ENSDARP00000092960 | ALMS1 centrosome and basal body-associated protein. | ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic intern [...] | 0.419 |
alms1 | cdh23 | ENSDARP00000098408 | ENSDARP00000026525 | ALMS1 centrosome and basal body-associated protein. | Cadherin-related 23. | 0.450 |
alms1 | cep290 | ENSDARP00000098408 | ENSDARP00000124972 | ALMS1 centrosome and basal body-associated protein. | Centrosomal protein of 290 kDa; Involved in early and late steps in cilia formation. May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs). In the ciliary transition zone is part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. Involved in regulation of the BBSome complex integrity and in ciliary targeting of selected BBSome cargos. Required for the correct localization of ciliary and photot [...] | 0.670 |
alms1 | ift88 | ENSDARP00000098408 | ENSDARP00000034047 | ALMS1 centrosome and basal body-associated protein. | Intraflagellar transport 88 homolog. | 0.571 |
arl13b | DYNC2H1 | ENSDARP00000092960 | ENSDARP00000152917 | ADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic intern [...] | Dynein cytoplasmic 2 heavy chain 1. | 0.562 |