Patched 1.

Bardet-Biedl syndrome 1.

Patched 1.

Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.

Patched 1.

GLI family zinc finger 2a.

Patched 1.

G-protein coupled receptor 161; Key negative regulator of Shh signaling during neural tube development. Recruited to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of gli3 into gli3r and repress the Shh signaling. In presence of shh, it is removed from primary cilia, preventing its activity and allowing activation of the Shh signaling (By similarity). Required in left/right patterning by modulating Ca(2+) levels in the cells surrounding the Kupffer vesicle; [...]

Patched 1.

Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia.

Patched 1.

Intraflagellar transport protein 57 homolog; Required for the formation of cilia. Essential for differentiation and survival of sensory neurons. May also have pro- apoptotic function.

Patched 1.

Intraflagellar transport 88 homolog.

Patched 1.

Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.

Patched 1.

Indian hedgehog B protein C-product; Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning and muscle pioneer differentiation.

Patched 1.

Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

Patched 1.

Kinesin-like protein kif7; Acts downstream of smo as an intracellular repressor of hedgehog signaling pathway, mainly through the suppression of gli1 activity. This negative regulatory effect is enhanced in conjunction with the suppressor of fused (sufu) protein. Positively regulates gli2a activity by promoting its dissociation from sufu. Involved in the regulation of microtubular dynamics.

Patched 1.

Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.

Patched 1.

Suppressor of fused homolog.

Arrestin, beta 1.

GLI family zinc finger 2a.

Arrestin, beta 1.

G-protein coupled receptor 161; Key negative regulator of Shh signaling during neural tube development. Recruited to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of gli3 into gli3r and repress the Shh signaling. In presence of shh, it is removed from primary cilia, preventing its activity and allowing activation of the Shh signaling (By similarity). Required in left/right patterning by modulating Ca(2+) levels in the cells surrounding the Kupffer vesicle; [...]

Arrestin, beta 1.

Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

Arrestin, beta 1.

Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.

Arrestin, beta 1.

Suppressor of fused homolog.

Bardet-Biedl syndrome 1.

Patched 1.

Bardet-Biedl syndrome 1.

Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.