STRINGSTRING
hsp70.3 hsp70.3 ctsl.1 ctsl.1 hsp90aa1.1 hsp90aa1.1 spata4 spata4 foxl2a foxl2a cts12 cts12 ccn4a ccn4a esr1 esr1 nanos3 nanos3 si:dkey-26g8.5 si:dkey-26g8.5 zgc:174855 zgc:174855 zgc:174154 zgc:174154 birc5a birc5a ctsla ctsla dmrt1 dmrt1 hsp70.1 hsp70.1 E7F8Y7_DANRE E7F8Y7_DANRE cyp19a1a cyp19a1a ctslb ctslb E9QBE2_DANRE E9QBE2_DANRE zgc:174153 zgc:174153 rps18 rps18 cdc20 cdc20 cdca8 cdca8 MGC174155 MGC174155 spag1a spag1a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hsp70.3Heat shock cognate 70-kd protein, tandem duplicate 3; Belongs to the heat shock protein 70 family. (643 aa)
ctsl.1Cathepsin L.1; Belongs to the peptidase C1 family. (334 aa)
hsp90aa1.1Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] (725 aa)
spata4Spermatogenesis-associated 4. (224 aa)
foxl2aForkhead box L2-1. (306 aa)
cts12Cathepsin 12; Belongs to the peptidase C1 family. (349 aa)
ccn4aCellular communication network factor 4a. (360 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. (569 aa)
nanos3Nanos homolog 3; Belongs to the nanos family. (159 aa)
si:dkey-26g8.5MGC174857 protein; Belongs to the peptidase C1 family. (335 aa)
zgc:174855Im:6910535 protein; Belongs to the peptidase C1 family. (335 aa)
zgc:174154Im:6910535; Belongs to the peptidase C1 family. (335 aa)
birc5aBaculoviral IAP repeat-containing 5a. (190 aa)
ctslaCathepsin La; Belongs to the peptidase C1 family. (337 aa)
dmrt1Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in sex determination and differentiation by controlling gonad development and germ cell proliferation. Acts both as a transcription repressor and activator (By similarity); Belongs to the DMRT family. (268 aa)
hsp70.1Heat shock cognate 70-kd protein, tandem duplicate 1; Belongs to the heat shock protein 70 family. (643 aa)
E7F8Y7_DANRESi:dkey-239j18.3; Belongs to the peptidase C1 family. (336 aa)
cyp19a1aAromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (517 aa)
ctslbCathepsin Lb; Belongs to the peptidase C1 family. (352 aa)
E9QBE2_DANRESi:dkey-239j18.2; Belongs to the peptidase C1 family. (335 aa)
zgc:174153Zgc:174153; Belongs to the peptidase C1 family. (336 aa)
rps1840S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA (By similarity). Plays an essential role in early embryonic development. (152 aa)
cdc20Cell division cycle 20 homolog. (496 aa)
cdca8Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (By similarity). (276 aa)
MGC174155Cathepsin Lb; Belongs to the peptidase C1 family. (336 aa)
spag1aSperm-associated antigen 1A; May play a role in the cytoplasmic assembly and/or trafficking of the axonemal dynein arms. (427 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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