STRINGSTRING
cfl2 cfl2 cfl1l cfl1l calm2a calm2a rhoab rhoab cfl1 cfl1 tgfb3 tgfb3 tgfbr2b tgfbr2b myh11a myh11a smad3a smad3a mylka mylka pfn2l pfn2l acta1b acta1b foxe3 foxe3 pfn2 pfn2 mat2aa mat2aa pfn1 pfn1 loxa loxa tgfbr1a tgfbr1a ppp1r12a ppp1r12a tgfb2 tgfb2 X1WCU6_DANRE X1WCU6_DANRE mfap5 mfap5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cfl2Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
cfl1lCofilin 1 (non-muscle),-like; Belongs to the actin-binding proteins ADF family. (163 aa)
calm2aCalmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
rhoabRho-related GTP-binding protein RhoA-B; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. (193 aa)
cfl1Muscle cofilin 2; Belongs to the actin-binding proteins ADF family. (165 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
tgfbr2bTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (556 aa)
myh11aMyosin, heavy polypeptide 11, smooth muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1974 aa)
smad3aMothers against decapentaplegic homolog. (425 aa)
mylkaMyosin, light chain kinase a. (899 aa)
pfn2lProfilin; Belongs to the profilin family. (139 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
foxe3Forkhead box E3. (422 aa)
pfn2Profilin; Belongs to the profilin family. (140 aa)
mat2aaS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (395 aa)
pfn1Profilin; Belongs to the profilin family. (141 aa)
loxaLysyl oxidase a. (408 aa)
tgfbr1aReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (500 aa)
ppp1r12aProtein phosphatase 1 regulatory subunit 12A; Regulates myosin phosphatase activity. (1117 aa)
tgfb2Transforming growth factor, beta 2. (413 aa)
X1WCU6_DANREProfilin; Belongs to the profilin family. (127 aa)
mfap5Microfibril-associated protein 5. (131 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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