STRINGSTRING
entpd8 entpd8 itga2b itga2b tpma tpma tpm4b tpm4b itgam itgam tpm2 tpm2 tpm3 tpm3 btk btk actn1 actn1 cd4-1 cd4-1 grna grna flna flna entpd3 entpd3 vwf vwf thpo thpo tubb1 tubb1 entpd1 entpd1 gapdh gapdh selp selp acta1b acta1b gapdhs gapdhs tpm4a tpm4a cfl1 cfl1 rhoab rhoab actn3b actn3b cfl1l cfl1l cfl2 cfl2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
entpd8Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (496 aa)
itga2bIntegrin, alpha 2b (Platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B); Belongs to the integrin alpha chain family. (1037 aa)
tpmaTropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments; Belongs to the tropomyosin family. (284 aa)
tpm4bTropomyosin 4b. (248 aa)
itgamIntegrin, alpha M (complement component 3 receptor 3 subunit); Belongs to the integrin alpha chain family. (780 aa)
tpm2Tropomyosin 2 (beta); Belongs to the tropomyosin family. (284 aa)
tpm3Tropomyosin 3; Belongs to the tropomyosin family. (284 aa)
btkTyrosine-protein kinase. (640 aa)
actn1Actinin, alpha 1. (902 aa)
cd4-1CD4-1 molecule. (474 aa)
grnaGranulin a. (1049 aa)
flnaFilamin A, alpha (actin-binding protein 280). (2553 aa)
entpd3Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (497 aa)
vwfVon Willebrand factor. (2812 aa)
thpoThrombopoietin. (191 aa)
tubb1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (466 aa)
entpd1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (492 aa)
gapdhGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] (333 aa)
selpSelectin P. (868 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
gapdhsGlyceraldehyde-3-phosphate dehydrogenase 2; Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. (335 aa)
tpm4aTropomyosin 4a; Belongs to the tropomyosin family. (284 aa)
cfl1Muscle cofilin 2; Belongs to the actin-binding proteins ADF family. (165 aa)
rhoabRho-related GTP-binding protein RhoA-B; Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. (193 aa)
actn3bActinin alpha 3b. (898 aa)
cfl1lCofilin 1 (non-muscle),-like; Belongs to the actin-binding proteins ADF family. (163 aa)
cfl2Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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