STRINGSTRING
hist2h2l hist2h2l dmd dmd hoxb4a hoxb4a myod1 myod1 myog myog rbfox1l rbfox1l pax3a pax3a rbfox2 rbfox2 mylpfa mylpfa rbfox1 rbfox1 pax7b pax7b myf5 myf5 loxa loxa grna grna X1WHF1_DANRE X1WHF1_DANRE pax7a pax7a smyhc1 smyhc1 rbfox3a rbfox3a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hist2h2lHistone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (126 aa)
dmdDystrophin. (594 aa)
hoxb4aHomeobox protein Hox-B4a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (246 aa)
myod1Myoblast determination protein 1 homolog; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. (275 aa)
myogMyogenin. (256 aa)
rbfox1lRNA binding protein fox-1 homolog 1-like; RNA-binding protein that regulates alternative splicing events by binding to 5'-GCAUG-3' elements. Regulates alternative splicing of tissue-specific exons. (382 aa)
pax3aTranscription factor PAX3. (509 aa)
rbfox2RNA-binding fox-1 homolog 2. (241 aa)
mylpfaMyosin light chain, phosphorylatable, fast skeletal muscle a. (169 aa)
rbfox1RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons (By similarity). (373 aa)
pax7bPaired box protein 7b. (510 aa)
myf5Myogenic factor. (237 aa)
loxaLysyl oxidase a. (408 aa)
grnaGranulin a. (1049 aa)
X1WHF1_DANREHistone H2B; Belongs to the histone H2B family. (124 aa)
pax7aTranscription factor PAX7C. (507 aa)
smyhc1Slow myosin heavy chain 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
rbfox3aRNA binding protein fox-1 homolog 3; RNA-binding protein that regulates alternative splicing events. (373 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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