STRINGSTRING
msna msna actn3b actn3b cfl1l cfl1l cfl2 cfl2 cfl1 cfl1 spast spast rab35b rab35b pfn2l pfn2l acta1b acta1b pxnb pxnb pfn2 pfn2 rabif rabif msnb msnb wee1 wee1 cdk1 cdk1 pfn1 pfn1 mical1 mical1 rab8a rab8a X1WCU6_DANRE X1WCU6_DANRE ltb4r ltb4r cdc42 cdc42 anln anln pxna pxna
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
msnaMoesin a. (579 aa)
actn3bActinin alpha 3b. (898 aa)
cfl1lCofilin 1 (non-muscle),-like; Belongs to the actin-binding proteins ADF family. (163 aa)
cfl2Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
cfl1Muscle cofilin 2; Belongs to the actin-binding proteins ADF family. (165 aa)
spastSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (570 aa)
rab35bRAB35, member RAS oncogene family b. (201 aa)
pfn2lProfilin; Belongs to the profilin family. (139 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
pxnbPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (525 aa)
pfn2Profilin; Belongs to the profilin family. (140 aa)
rabifRAB-interacting factor. (132 aa)
msnbMoesin b. (577 aa)
wee1Wee1-like protein kinase. (612 aa)
cdk1Cell division control protein 2; Belongs to the protein kinase superfamily. (302 aa)
pfn1Profilin; Belongs to the profilin family. (141 aa)
mical1[F-actin]-monooxygenase mical1; Monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin to form methionine-sulfoxide, resulting in actin filament disassembly and prevent repolymerization; Belongs to the Mical family. (1227 aa)
rab8aRAB8A, member RAS oncogene family. (207 aa)
X1WCU6_DANREProfilin; Belongs to the profilin family. (127 aa)
ltb4rLeukotriene B4 receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
cdc42Cell division cycle 42. (191 aa)
anlnAnillin, actin-binding protein. (1171 aa)
pxnaPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (532 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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