Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| abca1a | abcg1 | ENSDARP00000132417 | ENSDARP00000087241 | ATP-binding cassette, sub-family A (ABC1), member 1A. | ATP-binding cassette, sub-family G (WHITE), member 1. | 0.496 |
| abca1a | apoeb | ENSDARP00000132417 | ENSDARP00000058964 | ATP-binding cassette, sub-family A (ABC1), member 1A. | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | 0.852 |
| abca1a | cav1 | ENSDARP00000132417 | ENSDARP00000141857 | ATP-binding cassette, sub-family A (ABC1), member 1A. | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | 0.406 |
| abca1a | dhcr24 | ENSDARP00000132417 | ENSDARP00000110651 | ATP-binding cassette, sub-family A (ABC1), member 1A. | 24-dehydrocholesterol reductase. | 0.419 |
| abca1a | dhcr7 | ENSDARP00000132417 | ENSDARP00000136120 | ATP-binding cassette, sub-family A (ABC1), member 1A. | 7-dehydrocholesterol reductase; Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC). | 0.562 |
| abca1a | insig1 | ENSDARP00000132417 | ENSDARP00000018378 | ATP-binding cassette, sub-family A (ABC1), member 1A. | Insulin-induced gene 1 protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. | 0.457 |
| abca1a | npc1 | ENSDARP00000132417 | ENSDARP00000144951 | ATP-binding cassette, sub-family A (ABC1), member 1A. | Niemann-Pick disease, type C1. | 0.593 |
| abca1a | nr1h3 | ENSDARP00000132417 | ENSDARP00000139970 | ATP-binding cassette, sub-family A (ABC1), member 1A. | Nuclear receptor subfamily 1, group H, member 3. | 0.976 |
| abca1a | srebf2 | ENSDARP00000132417 | ENSDARP00000087122 | ATP-binding cassette, sub-family A (ABC1), member 1A. | Processed sterol regulatory element-binding protein 2; Transcriptional activator required for lipid homeostasis. May regulate transcription of the LDL receptor gene as well as the cholesterol and fatty acid synthesis pathways. Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes (By similarity). | 0.846 |
| abcg1 | abca1a | ENSDARP00000087241 | ENSDARP00000132417 | ATP-binding cassette, sub-family G (WHITE), member 1. | ATP-binding cassette, sub-family A (ABC1), member 1A. | 0.496 |
| abcg1 | apoeb | ENSDARP00000087241 | ENSDARP00000058964 | ATP-binding cassette, sub-family G (WHITE), member 1. | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | 0.812 |
| abcg1 | npc1 | ENSDARP00000087241 | ENSDARP00000144951 | ATP-binding cassette, sub-family G (WHITE), member 1. | Niemann-Pick disease, type C1. | 0.635 |
| abcg1 | nr1h3 | ENSDARP00000087241 | ENSDARP00000139970 | ATP-binding cassette, sub-family G (WHITE), member 1. | Nuclear receptor subfamily 1, group H, member 3. | 0.868 |
| abcg1 | srebf2 | ENSDARP00000087241 | ENSDARP00000087122 | ATP-binding cassette, sub-family G (WHITE), member 1. | Processed sterol regulatory element-binding protein 2; Transcriptional activator required for lipid homeostasis. May regulate transcription of the LDL receptor gene as well as the cholesterol and fatty acid synthesis pathways. Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes (By similarity). | 0.844 |
| apoeb | abca1a | ENSDARP00000058964 | ENSDARP00000132417 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | ATP-binding cassette, sub-family A (ABC1), member 1A. | 0.852 |
| apoeb | abcg1 | ENSDARP00000058964 | ENSDARP00000087241 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | ATP-binding cassette, sub-family G (WHITE), member 1. | 0.812 |
| apoeb | cav1 | ENSDARP00000058964 | ENSDARP00000141857 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. | 0.517 |
| apoeb | npc1 | ENSDARP00000058964 | ENSDARP00000144951 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | Niemann-Pick disease, type C1. | 0.506 |
| apoeb | nr1h3 | ENSDARP00000058964 | ENSDARP00000139970 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | Nuclear receptor subfamily 1, group H, member 3. | 0.748 |
| apoeb | shha | ENSDARP00000058964 | ENSDARP00000125090 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.406 |
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