Your Input: | |||||
casp3a | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (282 aa) | ||||
gli2a | GLI family zinc finger 2a. (1439 aa) | ||||
smo | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (822 aa) | ||||
prkacba | Protein kinase, cAMP-dependent, catalytic, beta a; Belongs to the protein kinase superfamily. (395 aa) | ||||
gsk3ba | Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (421 aa) | ||||
kif7 | Kinesin-like protein kif7; Acts downstream of smo as an intracellular repressor of hedgehog signaling pathway, mainly through the suppression of gli1 activity. This negative regulatory effect is enhanced in conjunction with the suppressor of fused (sufu) protein. Positively regulates gli2a activity by promoting its dissociation from sufu. Involved in the regulation of microtubular dynamics. (1363 aa) | ||||
angpt1 | Angiopoietin 1. (513 aa) | ||||
acta1b | Actin alpha 1, skeletal muscle b. (377 aa) | ||||
gli3 | GLI family zinc finger 3. (1553 aa) | ||||
egf | Epidermal growth factor. (1114 aa) | ||||
casp3b | Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. (285 aa) | ||||
ihhb | Indian hedgehog B protein C-product; Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning and muscle pioneer differentiation. (412 aa) | ||||
prkacbb | Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa) | ||||
hhip | Hedgehog-interacting protein. (693 aa) | ||||
boc | BOC cell adhesion-associated, oncogene-regulated. (1032 aa) | ||||
twist2 | Twist2. (163 aa) | ||||
gpc1a | Secreted glypican-1; Cell surface proteoglycan that bears heparan sulfate; Belongs to the glypican family. (563 aa) | ||||
shha | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). (418 aa) | ||||
sufu | Suppressor of fused homolog. (485 aa) | ||||
prkacaa | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (352 aa) | ||||
gpc3 | Glypican-3 alpha subunit; Cell surface proteoglycan that bears heparan sulfate (By similarity). Negatively regulates the hedgehog signaling pathway (By similarity). Positively regulates the canonical and non-canonical Wnt signaling pathways (By similarity). Binds to CD81 which decreases the availability of free CD81 for binding to the transcriptional repressor HHEX, resulting in nuclear translocation of HHEX and transcriptional repression (By similarity). Inhibits the dipeptidyl peptidase activity of DPP4 (By similarity). Plays a role in limb patterning and skeletal development (By sim [...] (590 aa) | ||||
angpt4 | Angiopoietin 4. (499 aa) | ||||
gpc1b | Glypican 1b; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (559 aa) | ||||
prkacab | Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (351 aa) | ||||
twist3 | Twist3. (199 aa) |