Patched 1.

Desert hedgehog protein; Intercellular signal essential for a variety of patterning events during development; Belongs to the hedgehog family.

Patched 1.

GLI family zinc finger 1.

Patched 1.

GLI family zinc finger 2a.

Patched 1.

Indian hedgehog B protein C-product; Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning and muscle pioneer differentiation.

Patched 1.

Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity).

Patched 1.

Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.

Patched 1.

Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression.

Actin alpha 1, skeletal muscle b.

GLI family zinc finger 1.

Actin alpha 1, skeletal muscle b.

Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.

Actin alpha 1, skeletal muscle b.

Transcriptional regulator Myc-A; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

Actin alpha 1, skeletal muscle b.

Myoblast determination protein 1 homolog; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.

Actin alpha 1, skeletal muscle b.

Protein patched homolog 1; Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity). Belongs to the patched family.

Actin alpha 1, skeletal muscle b.

Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity).

Actin alpha 1, skeletal muscle b.

Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.

Actin alpha 1, skeletal muscle b.

Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression.

Desert hedgehog protein; Intercellular signal essential for a variety of patterning events during development; Belongs to the hedgehog family.

Patched 1.

Desert hedgehog protein; Intercellular signal essential for a variety of patterning events during development; Belongs to the hedgehog family.

GLI family zinc finger 1.

Desert hedgehog protein; Intercellular signal essential for a variety of patterning events during development; Belongs to the hedgehog family.

GLI family zinc finger 2a.

Desert hedgehog protein; Intercellular signal essential for a variety of patterning events during development; Belongs to the hedgehog family.

Protein patched homolog 1.

Desert hedgehog protein; Intercellular signal essential for a variety of patterning events during development; Belongs to the hedgehog family.

Protein patched homolog 1; Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity). Belongs to the patched family.