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mtor | Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2563 aa) | ||||
myod1 | Myoblast determination protein 1 homolog; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. (275 aa) | ||||
gli2a | GLI family zinc finger 2a. (1439 aa) | ||||
smo | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (822 aa) | ||||
prkg1a | cGMP-dependent protein kinase. (667 aa) | ||||
ptch1 | Protein patched homolog 1. (1475 aa) | ||||
dhh | Desert hedgehog protein; Intercellular signal essential for a variety of patterning events during development; Belongs to the hedgehog family. (447 aa) | ||||
acta1b | Actin alpha 1, skeletal muscle b. (377 aa) | ||||
jun | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (308 aa) | ||||
prkg2 | cGMP-dependent protein kinase. (768 aa) | ||||
ptch2 | Protein patched homolog 1; Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity). Belongs to the patched family. (1442 aa) | ||||
ihhb | Indian hedgehog B protein C-product; Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning and muscle pioneer differentiation. (412 aa) | ||||
dyrk4 | Dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 4. (634 aa) | ||||
myca | Transcriptional regulator Myc-A; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (409 aa) | ||||
dyrk3 | Dual-specificity tyrosine phosphorylation-regulated kinase 3. (582 aa) | ||||
tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. (369 aa) | ||||
dyrk2 | Dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 2. (587 aa) | ||||
ENSDARP00000125042 | Patched 1. (120 aa) | ||||
shha | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). (418 aa) | ||||
gli1 | GLI family zinc finger 1. (1404 aa) | ||||
prkg1b | cGMP-dependent protein kinase. (684 aa) |