Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acta1b | axin1 | ENSDARP00000058628 | ENSDARP00000135613 | Actin alpha 1, skeletal muscle b. | Axin-1; Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects: down- regulates ctnnb1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. | 0.494 |
| acta1b | ctnnb1 | ENSDARP00000058628 | ENSDARP00000139205 | Actin alpha 1, skeletal muscle b. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.967 |
| acta1b | egf | ENSDARP00000058628 | ENSDARP00000069126 | Actin alpha 1, skeletal muscle b. | Epidermal growth factor. | 0.840 |
| acta1b | gapdh | ENSDARP00000058628 | ENSDARP00000063799 | Actin alpha 1, skeletal muscle b. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] | 0.970 |
| acta1b | gapdhs | ENSDARP00000058628 | ENSDARP00000058383 | Actin alpha 1, skeletal muscle b. | Glyceraldehyde-3-phosphate dehydrogenase 2; Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. | 0.940 |
| acta1b | gsk3ba | ENSDARP00000058628 | ENSDARP00000027785 | Actin alpha 1, skeletal muscle b. | Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. | 0.700 |
| acta1b | lamp1b | ENSDARP00000058628 | ENSDARP00000123215 | Actin alpha 1, skeletal muscle b. | Lysosomal-associated membrane protein 1b. | 0.682 |
| acta1b | lrp6 | ENSDARP00000058628 | ENSDARP00000135077 | Actin alpha 1, skeletal muscle b. | Low density lipoprotein receptor-related protein 6. | 0.453 |
| acta1b | smad4a | ENSDARP00000058628 | ENSDARP00000097763 | Actin alpha 1, skeletal muscle b. | Mothers against decapentaplegic homolog. | 0.597 |
| acta1b | wnt3a | ENSDARP00000058628 | ENSDARP00000089165 | Actin alpha 1, skeletal muscle b. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.644 |
| acta1b | wu:fi04e12 | ENSDARP00000058628 | ENSDARP00000103914 | Actin alpha 1, skeletal muscle b. | Wu:fi04e12. | 0.595 |
| axin1 | acta1b | ENSDARP00000135613 | ENSDARP00000058628 | Axin-1; Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects: down- regulates ctnnb1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. | Actin alpha 1, skeletal muscle b. | 0.494 |
| axin1 | ctnnb1 | ENSDARP00000135613 | ENSDARP00000139205 | Axin-1; Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects: down- regulates ctnnb1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.999 |
| axin1 | egf | ENSDARP00000135613 | ENSDARP00000069126 | Axin-1; Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects: down- regulates ctnnb1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. | Epidermal growth factor. | 0.507 |
| axin1 | gapdh | ENSDARP00000135613 | ENSDARP00000063799 | Axin-1; Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects: down- regulates ctnnb1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] | 0.413 |
| axin1 | gapdhs | ENSDARP00000135613 | ENSDARP00000058383 | Axin-1; Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects: down- regulates ctnnb1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. | Glyceraldehyde-3-phosphate dehydrogenase 2; Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. | 0.404 |
| axin1 | gsk3ba | ENSDARP00000135613 | ENSDARP00000027785 | Axin-1; Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects: down- regulates ctnnb1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. | Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. | 0.999 |
| axin1 | lrp6 | ENSDARP00000135613 | ENSDARP00000135077 | Axin-1; Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects: down- regulates ctnnb1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. | Low density lipoprotein receptor-related protein 6. | 0.982 |
| axin1 | smad4a | ENSDARP00000135613 | ENSDARP00000097763 | Axin-1; Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects: down- regulates ctnnb1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. | Mothers against decapentaplegic homolog. | 0.540 |
| axin1 | wnt3a | ENSDARP00000135613 | ENSDARP00000089165 | Axin-1; Component of the beta-catenin destruction complex required for regulating ctnnb1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects: down- regulates ctnnb1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.951 |
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