STRINGSTRING
pfn1 pfn1 marcksa marcksa pfn2 pfn2 src src scinlb scinlb rab10 rab10 syn2a syn2a acta1b acta1b pfn2l pfn2l gsnb gsnb scin scin ptk2ab ptk2ab cdh2 cdh2 cfl1l cfl1l cfl2 cfl2 erbb2 erbb2 calm2a calm2a cfl1 cfl1 gsna gsna ntn1b ntn1b ctnnb1 ctnnb1 scinla scinla gap43 gap43 ntn1a ntn1a syn2b syn2b cdc42 cdc42 X1WCU6_DANRE X1WCU6_DANRE ntn2 ntn2 syn1 syn1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pfn1Profilin; Belongs to the profilin family. (141 aa)
marcksaMyristoylated alanine-rich protein kinase C substrate a. (236 aa)
pfn2Profilin; Belongs to the profilin family. (140 aa)
srcProto-oncogene tyrosine-protein kinase Src; Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy bet [...] (534 aa)
scinlbScinderin-like b. (720 aa)
rab10RAB10, member RAS oncogene family. (201 aa)
syn2aSynapsin IIa. (463 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
pfn2lProfilin; Belongs to the profilin family. (139 aa)
gsnbGelsolin b. (728 aa)
scinScinderin. (733 aa)
ptk2abProtein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1050 aa)
cdh2Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion (By similarity). Cadherins contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development. Required for normal neural tube morphogenesis. Required to allow mid- and hindbrain neurons to reach and maintain their appropriate positions within the neural tube by restricting neuronal motility within the embryonic mid- and hindbrain. (893 aa)
cfl1lCofilin 1 (non-muscle),-like; Belongs to the actin-binding proteins ADF family. (163 aa)
cfl2Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
erbb2Receptor protein-tyrosine kinase. (1275 aa)
calm2aCalmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
cfl1Muscle cofilin 2; Belongs to the actin-binding proteins ADF family. (165 aa)
gsnaGelsolin a. (729 aa)
ntn1bNetrin 1b. (602 aa)
ctnnb1Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] (789 aa)
scinlaScinderin-like a. (720 aa)
gap43Growth-associated protein 43. (194 aa)
ntn1aNetrin-1a. (603 aa)
syn2bSynapsin IIb. (695 aa)
cdc42Cell division cycle 42. (191 aa)
X1WCU6_DANREProfilin; Belongs to the profilin family. (127 aa)
ntn2Netrin 2. (609 aa)
syn1Synapsin I. (670 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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