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tgfb1b | Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa) | ||||
sox4a | Transcription factor SOX. (363 aa) | ||||
pou4f1 | POU domain protein. (368 aa) | ||||
mycb | Transcriptional regulator Myc-B; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (396 aa) | ||||
bdnf | Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (270 aa) | ||||
ptf1a | Pancreas transcription factor 1 subunit alpha; Transcription factor implicated in the cell fate determination in various organs. Binds to the E-box consensus sequence 5'-CANNTG-3'. Required for exocrine pancreatic development. Plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates. (265 aa) | ||||
isl1 | Insulin gene enhancer protein isl-1; DNA-binding transcriptional activator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. May be involved in subtype specialization of primary motoneurons. May bind to insulin gene enhancer sequences. Essential for heart development (By similarity). (349 aa) | ||||
foxn4 | Forkhead box protein N4; Transcription factor essential for neural and some non-neural tissues development. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates. Drives commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the [...] (550 aa) | ||||
tgfb3 | Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa) | ||||
isl1l | Islet1,-like. (323 aa) | ||||
neurod1 | Neurogenic differentiation factor 1; May act as a transcriptional activator. Differentiation factor required for neurogenesis. Acts as an upstream activator of isl1. (350 aa) | ||||
onecut1 | One cut domain family member. (461 aa) | ||||
elavl3 | ELAV-like protein; Belongs to the RRM elav family. (359 aa) | ||||
vsx2 | Visual system homeobox 2; Acts as a transcriptional regulator (By similarity). Mediates the differentiation of V2a interneurons (By similarity). Plays a role in eye development and organization of the neuroretina. (372 aa) | ||||
socs3a | Suppressor of cytokine-signaling 3a. (207 aa) | ||||
fosab | V-fos FBJ murine osteosarcoma viral oncogene homolog Ab. (349 aa) | ||||
slit1b | Slit homolog 1b (Drosophila). (1532 aa) | ||||
sncgb | Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family. (114 aa) | ||||
shha | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). (418 aa) | ||||
pou4f3 | POU domain, class 4, transcription factor 3; Acts as a transcriptional activator. Acts by binding to sequences related to the consensus octamer motif 5'-ATGCAAAT-3' in the regulatory regions of its target genes. May play a role in specifying terminally differentiated neuronal phenotypes. (331 aa) | ||||
gdnfa | Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake (By similarity). Essential for the development of the enteric nervous system, but appears dispensable for the development of the kidney and primary motor neuron; Belongs to the TGF-beta family. GDNF subfamily. (235 aa) | ||||
onecutl | One cut domain family member. (450 aa) | ||||
fsta | Follistatin-A; Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (fsh) (By similarity). Inhibits bmp-signaling during later stages of development including late phases of dorsoventral patterning, to refine the early pattern set up by the interaction of chordino and bmp2/4. Not involved in organizer function or early phases of dorsoventral pattern formation. (324 aa) | ||||
sncga | Synuclein, gamma a; Belongs to the synuclein family. (111 aa) | ||||
m17 | IL-6 subfamily cytokine M17. (219 aa) | ||||
casz1 | Castor zinc finger 1. (1644 aa) | ||||
map2 | Microtubule-associated protein 2. (248 aa) | ||||
pou4f2 | POU domain protein. (384 aa) | ||||
slit1a | Slit homolog 1a (Drosophila). (1524 aa) | ||||
myca | Transcriptional regulator Myc-A; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (409 aa) | ||||
klf4 | Kruppel-like factor 4. (340 aa) | ||||
tgfb5 | Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa) | ||||
atoh7 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. (134 aa) | ||||
ntf3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (243 aa) | ||||
six3a | Sine oculis homeobox homolog 3a. (294 aa) | ||||
fstb | Follistatin 2. (344 aa) | ||||
ikzf1 | IKAROS family zinc finger 1 (Ikaros). (526 aa) | ||||
ptenb | Phosphatase and tensin homolog B; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (422 aa) | ||||
six3b | Sine oculis homeobox homolog 3b. (293 aa) | ||||
pou5f3 | POU domain, class 5, transcription factor 1; Involved in early development of embryos, especially in the process of gastrulation. May play an important role in establishing and specifying rhombomeric segments. Seems to be required to maintain the cells in a highly undifferentiated state. In contrast to POU2, T-POU2 lacks DNA-binding activity because of its incomplete pou domain structure. Overexpression of POU2 does not have any effect on development, whereas overexpression of t-POU2 causes developmental retardation or arrest before gastrulation; Belongs to the POU transcription factor [...] (472 aa) | ||||
tgfb1a | Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa) | ||||
calb2a | Calbindin 2, like. (271 aa) | ||||
shhb | Tiggy-winkle hedgehog protein C-product; Intercellular signal essential for a variety of patterning events during development. Involved in dorso-ventral patterning of the brain and in early patterning of the developing eyes. (416 aa) | ||||
klf17 | Kruppel-like factor 17. (409 aa) | ||||
calb2b | Calbindin 2b. (269 aa) |