STRINGSTRING
map3k7 map3k7 mhc2b mhc2b ENSDARP00000137499 ENSDARP00000137499 irf5 irf5 irak4 irak4 itgam itgam rela rela tbk1 tbk1 il6 il6 ticam1 ticam1 relb relb irf3 irf3 nfkb2 nfkb2 il15 il15 atr atr usf2 usf2 cebpd cebpd lectin lectin myca myca il10 il10 cnbpb cnbpb irf7 irf7 mhc2bl mhc2bl rel rel pgk1 pgk1 egf egf cnbpa cnbpa il17a/f2 il17a/f2 il17a/f1 il17a/f1 gapdh gapdh cebpb cebpb il17a/f3 il17a/f3 gapdhs gapdhs cebpa cebpa med21 med21 cgas cgas rbpms2b rbpms2b myd88 myd88 tlr3 tlr3 ifih1 ifih1 tnfb tnfb usf1l usf1l
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
map3k7Mitogen-activated protein kinase kinase kinase 7. (551 aa)
mhc2bMajor histocompatibility complex class II integral membrane beta chain gene. (252 aa)
ENSDARP00000137499Si:dkey-33b17.3. (277 aa)
irf5Interferon regulatory factor 5. (516 aa)
irak4Interleukin-1 receptor-associated kinase 4. (447 aa)
itgamIntegrin, alpha M (complement component 3 receptor 3 subunit); Belongs to the integrin alpha chain family. (780 aa)
relaV-rel avian reticuloendotheliosis viral oncogene homolog A. (455 aa)
tbk1TANK-binding kinase 1. (727 aa)
il6Interleukin 6 (interferon, beta 2). (231 aa)
ticam1Toll-like receptor adaptor molecule 1. (566 aa)
relbV-rel avian reticuloendotheliosis viral oncogene homolog B. (582 aa)
irf3Interferon regulatory factor 3. (426 aa)
nfkb2Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100). (902 aa)
il15Interleukin; Belongs to the IL-15/IL-21 family. (193 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2635 aa)
usf2Upstream transcription factor 2, c-fos-interacting. (328 aa)
cebpdCCAAT/enhancer-binding protein. (280 aa)
lectinLectin. (152 aa)
mycaTranscriptional regulator Myc-A; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (409 aa)
il10Interleukin-10. (180 aa)
cnbpbCCHC-type zinc finger, nucleic acid-binding protein b. (161 aa)
irf7Interferon regulatory factor 7. (422 aa)
mhc2blMHC class II beta chain-like. (250 aa)
relV-rel avian reticuloendotheliosis viral oncogene homolog. (596 aa)
pgk1Phosphoglycerate kinase. (417 aa)
egfEpidermal growth factor. (1114 aa)
cnbpaCCHC-type zinc finger, nucleic acid-binding protein a. (163 aa)
il17a/f2Interleukin 17a/f2. (140 aa)
il17a/f1Interleukin 17a/f1. (153 aa)
gapdhGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] (333 aa)
cebpbCCAAT/enhancer-binding protein. (280 aa)
il17a/f3Interleukin 17a/f3. (162 aa)
gapdhsGlyceraldehyde-3-phosphate dehydrogenase 2; Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. (335 aa)
cebpaCCAAT/enhancer-binding protein. (288 aa)
med21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (145 aa)
cgasCyclic GMP-AMP synthase. (592 aa)
rbpms2bRNA-binding protein, mRNA-processing factor 2b. (200 aa)
myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. (284 aa)
tlr3Toll-like receptor 3; Belongs to the Toll-like receptor family. (903 aa)
ifih1Interferon-induced with helicase C domain 1. (997 aa)
tnfbTumor necrosis factor b (TNF superfamily, member 2). (242 aa)
usf1lUpstream transcription factor 2, c-fos interacting. (283 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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