STRINGSTRING
ccr2 ccr2 ccr2-2 ccr2-2 il1b il1b nos1 nos1 itgam itgam gata4 gata4 nos2a nos2a il13 il13 mef2ca mef2ca il10 il10 mapk3 mapk3 kita kita foxp3a foxp3a angpt2b angpt2b mmp9 mmp9 cxcr4b cxcr4b cxcl12a cxcl12a nos2b nos2b mpx mpx angpt1 angpt1 thpo thpo nkx2.5 nkx2.5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ccr2Chemokine (C-C motif) receptor 2; Belongs to the G-protein coupled receptor 1 family. (354 aa)
ccr2-2Chemokine (C-C motif) receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa)
il1bInterleukin-1. (284 aa)
nos1Nitric oxide synthase; Produces nitric oxide (NO). (1431 aa)
itgamIntegrin, alpha M (complement component 3 receptor 3 subunit); Belongs to the integrin alpha chain family. (780 aa)
gata4GATA-binding protein 4. (352 aa)
nos2aNitric oxide synthase; Produces nitric oxide (NO). (1079 aa)
il13Interleukin 4/13A. (157 aa)
mef2caMyocyte enhancer factor 2ca. (465 aa)
il10Interleukin-10. (180 aa)
mapk3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (392 aa)
kitaMast/stem cell growth factor receptor kita; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine kitlg/scf and plays a role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, and in mast cell development, migration and function. Required for the migration of cells in the melanocyte lineage and the survival of embryonic melanocytes. Required for the differentiation of some, but not all, melanocytes. Not essential for hematopoiesis or primordial germ cell development. (981 aa)
foxp3aForkhead box protein. (419 aa)
angpt2bAngiopoietin 2b. (489 aa)
mmp9Matrix metallopeptidase 9. (680 aa)
cxcr4bChemokine (C-X-C motif), receptor 4b; Belongs to the G-protein coupled receptor 1 family. (353 aa)
cxcl12aChemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1); Belongs to the intercrine alpha (chemokine CxC) family. (99 aa)
nos2bNitric oxide synthase; Produces nitric oxide (NO). (1077 aa)
mpxMyeloid-specific peroxidase. (893 aa)
angpt1Angiopoietin 1. (513 aa)
thpoThrombopoietin. (191 aa)
nkx2.5NK2 homeobox 5. (314 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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