STRINGSTRING
pyya pyya sim1b sim1b bdnf bdnf acin1b acin1b sim1a sim1a ins ins psap psap lepr lepr manf manf stat3 stat3 cdnf cdnf mtor mtor insb insb cntf cntf ghrl ghrl il6 il6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pyyaPeptide YY-A; Belongs to the NPY family. (97 aa)
sim1bSIM bHLH transcription factor 1b. (586 aa)
bdnfBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (270 aa)
acin1bApoptotic chromatin condensation inducer 1b. (1259 aa)
sim1aSingle-minded homolog 1-A; Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult. (745 aa)
insInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa)
psapProsaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (520 aa)
leprLeptin receptor. (1065 aa)
manfMesencephalic astrocyte-derived neurotrophic factor. (180 aa)
stat3Signal transducer and activator of transcription. (806 aa)
cdnfCerebral dopamine neurotrophic factor. (182 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2563 aa)
insbInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (159 aa)
cntfCiliary neurotrophic factor. (195 aa)
ghrlGhrelin/obestatin prepropeptide. (104 aa)
il6Interleukin 6 (interferon, beta 2). (231 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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