STRINGSTRING
sox9a sox9a nr5a2 nr5a2 irf6 irf6 faslg faslg foxo1a foxo1a fgf2 fgf2 hemgn hemgn bcl2a bcl2a grna grna sox18 sox18 cyp19a1a cyp19a1a dmrt1 dmrt1 pmaip1 pmaip1 nr0b1 nr0b1 foxl2b foxl2b ar ar sox3 sox3 gapdh gapdh foxl2a foxl2a gapdhs gapdhs fgf24 fgf24 bmp15 bmp15 tspo tspo baxa baxa mettl3 mettl3 amh amh casp3a casp3a gdf9 gdf9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sox9aHMG box transcription factor Sox9a. (462 aa)
nr5a2Nuclear receptor subfamily 5, group A, member 2. (517 aa)
irf6Interferon regulatory factor 6. (492 aa)
faslgFas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (268 aa)
foxo1aForkhead box protein O1-A; Transcriptional regulator of cell cycle arrest required for cellular stress responses (By similarity). May be involved in regulating cellular homeostasis in the eye. (652 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa)
hemgnHemogen. (198 aa)
bcl2aB-cell leukemia/lymphoma 2. (228 aa)
grnaGranulin a. (1049 aa)
sox18SRY-box transcription factor 18. (431 aa)
cyp19a1aAromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (517 aa)
dmrt1Doublesex- and mab-3-related transcription factor 1; Transcription factor that plays a key role in sex determination and differentiation by controlling gonad development and germ cell proliferation. Acts both as a transcription repressor and activator (By similarity); Belongs to the DMRT family. (268 aa)
pmaip1Phorbol-12-myristate-13-acetate-induced protein 1. (45 aa)
nr0b1Nuclear receptor subfamily 0, group B, member 1. (302 aa)
foxl2bForkhead box L2-like protein. (285 aa)
arAndrogen receptor. (868 aa)
sox3Transcription factor Sox-3; Transcriptional activator. (300 aa)
gapdhGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] (333 aa)
foxl2aForkhead box L2-1. (306 aa)
gapdhsGlyceraldehyde-3-phosphate dehydrogenase 2; Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. (335 aa)
fgf24Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
bmp15Bone morphogenetic protein 15. (384 aa)
tspoTranslocator protein. (162 aa)
baxaBCL2-associated X, apoptosis regulator a. (192 aa)
mettl3N6-adenosine-methyltransferase subunit METTL3; The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some RNAs and regulates various processes such as the circadian clock, differentiation of embryonic and hematopoietic stem cells, cortical neurogenesis, response to DNA damage, differentiation of T-cells and primary miRNA processing. In the heterodimer formed with mettl14, mettl3 constitutes the catalytic core (By similarity). N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some [...] (584 aa)
amhAnti-Mullerian hormone. (549 aa)
casp3aCaspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (282 aa)
gdf9Growth differentiation factor 9. (418 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.