node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
abhd12 | cdh23 | ENSDARP00000095479 | ENSDARP00000026525 | Lysophosphatidylserine lipase ABHD12; Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes (By similarity). Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system (By similarity). Also able to hydrolyze oxidized phosphatidylserine; oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal. Also has monoacylglycerol (MAG) lipase act [...] | Cadherin-related 23. | 0.560 |
abhd12 | cdh23-2 | ENSDARP00000095479 | ENSDARP00000119218 | Lysophosphatidylserine lipase ABHD12; Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes (By similarity). Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system (By similarity). Also able to hydrolyze oxidized phosphatidylserine; oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal. Also has monoacylglycerol (MAG) lipase act [...] | Cadherin-related 23. | 0.663 |
abhd12 | cib2 | ENSDARP00000095479 | ENSDARP00000130315 | Lysophosphatidylserine lipase ABHD12; Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes (By similarity). Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system (By similarity). Also able to hydrolyze oxidized phosphatidylserine; oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal. Also has monoacylglycerol (MAG) lipase act [...] | Calcium and integrin-binding family member 2. | 0.644 |
abhd12 | clrn1 | ENSDARP00000095479 | ENSDARP00000140380 | Lysophosphatidylserine lipase ABHD12; Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes (By similarity). Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system (By similarity). Also able to hydrolyze oxidized phosphatidylserine; oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal. Also has monoacylglycerol (MAG) lipase act [...] | Clrn1 protein. | 0.609 |
abhd12 | ush1gb | ENSDARP00000095479 | ENSDARP00000156275 | Lysophosphatidylserine lipase ABHD12; Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes (By similarity). Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system (By similarity). Also able to hydrolyze oxidized phosphatidylserine; oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal. Also has monoacylglycerol (MAG) lipase act [...] | Usher syndrome 1Gb (autosomal recessive). | 0.568 |
abhd12 | ush2a | ENSDARP00000095479 | ENSDARP00000080636 | Lysophosphatidylserine lipase ABHD12; Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes (By similarity). Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system (By similarity). Also able to hydrolyze oxidized phosphatidylserine; oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal. Also has monoacylglycerol (MAG) lipase act [...] | Usher syndrome 2A (autosomal recessive, mild). | 0.483 |
acta1b | cdh23 | ENSDARP00000058628 | ENSDARP00000026525 | Actin alpha 1, skeletal muscle b. | Cadherin-related 23. | 0.687 |
acta1b | cib2 | ENSDARP00000058628 | ENSDARP00000130315 | Actin alpha 1, skeletal muscle b. | Calcium and integrin-binding family member 2. | 0.440 |
acta1b | ezrb | ENSDARP00000058628 | ENSDARP00000073352 | Actin alpha 1, skeletal muscle b. | Ezrin b. | 0.991 |
acta1b | msna | ENSDARP00000058628 | ENSDARP00000017246 | Actin alpha 1, skeletal muscle b. | Moesin a. | 0.989 |
acta1b | myo7aa | ENSDARP00000058628 | ENSDARP00000143601 | Actin alpha 1, skeletal muscle b. | Myosin VIIAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.919 |
acta1b | src | ENSDARP00000058628 | ENSDARP00000093618 | Actin alpha 1, skeletal muscle b. | Proto-oncogene tyrosine-protein kinase Src; Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy bet [...] | 0.876 |
acta1b | ush1c | ENSDARP00000058628 | ENSDARP00000104974 | Actin alpha 1, skeletal muscle b. | Usher syndrome 1C (Autosomal recessive, severe). | 0.596 |
acta1b | ush2a | ENSDARP00000058628 | ENSDARP00000080636 | Actin alpha 1, skeletal muscle b. | Usher syndrome 2A (autosomal recessive, mild). | 0.417 |
acta1b | whrna | ENSDARP00000058628 | ENSDARP00000102025 | Actin alpha 1, skeletal muscle b. | Whirlin a. | 0.496 |
adgrv1 | cdh23 | ENSDARP00000020853 | ENSDARP00000026525 | Adhesion G-protein coupled receptor V1; Receptor that may have an important role in the development of the sensory nervous system. | Cadherin-related 23. | 0.933 |
adgrv1 | cdh23-2 | ENSDARP00000020853 | ENSDARP00000119218 | Adhesion G-protein coupled receptor V1; Receptor that may have an important role in the development of the sensory nervous system. | Cadherin-related 23. | 0.912 |
adgrv1 | cib2 | ENSDARP00000020853 | ENSDARP00000130315 | Adhesion G-protein coupled receptor V1; Receptor that may have an important role in the development of the sensory nervous system. | Calcium and integrin-binding family member 2. | 0.864 |
adgrv1 | clrn1 | ENSDARP00000020853 | ENSDARP00000140380 | Adhesion G-protein coupled receptor V1; Receptor that may have an important role in the development of the sensory nervous system. | Clrn1 protein. | 0.875 |
adgrv1 | myo7aa | ENSDARP00000020853 | ENSDARP00000143601 | Adhesion G-protein coupled receptor V1; Receptor that may have an important role in the development of the sensory nervous system. | Myosin VIIAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.873 |