STRINGSTRING
gata4 gata4 myl2b myl2b myf5 myf5 sdf4 sdf4 acta1b acta1b myf6 myf6 myl7 myl7 myl4 myl4 tbx5a tbx5a hand2 hand2 nkx2.5 nkx2.5 myog myog myod1 myod1 mmp2 mmp2 myl1 myl1 pax3a pax3a pax7a pax7a gata6 gata6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gata4GATA-binding protein 4. (352 aa)
myl2bMyosin, light polypeptide 2, regulatory, cardiac, slow. (168 aa)
myf5Myogenic factor. (237 aa)
sdf445 kDa calcium-binding protein; May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment; Belongs to the CREC family. (356 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
myf6Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). (239 aa)
myl7Myosin, light polypeptide 7, regulatory. (172 aa)
myl4Myosin, light chain 4, alkali; atrial, embryonic. (187 aa)
tbx5aT-box transcription factor TBX5-A; Required for pectoral fin formation. Together with tbx5b, involved in eye and heart development. Required for the looping stage of heart development. May bind to the core DNA motif of promoters. (492 aa)
hand2Heart- and neural crest derivatives-expressed protein 2; Essential for myocardial and pectoral fin differentiation, patterning and morphogenesis. (205 aa)
nkx2.5NK2 homeobox 5. (314 aa)
myogMyogenin. (256 aa)
myod1Myoblast determination protein 1 homolog; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. (275 aa)
mmp2Matrix metalloproteinase 2. (657 aa)
myl1Myosin, light chain 1, alkali; skeletal, fast; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. (190 aa)
pax3aTranscription factor PAX3. (509 aa)
pax7aTranscription factor PAX7C. (507 aa)
gata6GATA-binding protein 6. (501 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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