STRINGSTRING
vegfaa vegfaa tnfb tnfb tnfrsf1a tnfrsf1a tlr4bb tlr4bb spi1b spi1b mpx mpx cxcl12a cxcl12a ccl38a.5 ccl38a.5 cxcr4b cxcr4b csf3r csf3r cxcr2 cxcr2 mpeg1.1 mpeg1.1 irf8 irf8 mfap4 mfap4 il10 il10 tlr4al tlr4al tlr4ba tlr4ba rac2 rac2 il34 il34 grna grna csf1rb csf1rb MFAP4 MFAP4 itgam itgam il1b il1b ccr2-2 ccr2-2 ccr2 ccr2 kras kras csf1ra csf1ra cxcr1 cxcr1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
vegfaaVascular endothelial growth factor A-A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis, and induces permeabilization of blood vessels. Acts both upstream of kdr and tie1 to stimulate endothelial cell differentiation, and upstream of gata1 to stimulate hematopoietic cell differentiation. (188 aa)
tnfbTumor necrosis factor b (TNF superfamily, member 2). (242 aa)
tnfrsf1aTumor necrosis factor receptor superfamily, member 1a. (389 aa)
tlr4bbToll-like receptor 4b, duplicate b. (819 aa)
spi1bSI:bY184L24.2.1 (Transcription factor spi1). (296 aa)
mpxMyeloid-specific peroxidase. (893 aa)
cxcl12aChemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1); Belongs to the intercrine alpha (chemokine CxC) family. (99 aa)
ccl38a.5C-C motif chemokine. (103 aa)
cxcr4bChemokine (C-X-C motif), receptor 4b; Belongs to the G-protein coupled receptor 1 family. (353 aa)
csf3rColony-stimulating factor 3 receptor (granulocyte). (810 aa)
cxcr2Chemokine (C-X-C motif) receptor 2; Belongs to the G-protein coupled receptor 1 family. (340 aa)
mpeg1.1Macrophage-expressed 1, tandem duplicate 1. (718 aa)
irf8Interferon regulatory factor 8. (423 aa)
mfap4Microfibril-associated protein 4. (242 aa)
il10Interleukin-10. (180 aa)
tlr4alToll-like receptor 4a, like. (816 aa)
tlr4baToll-like receptor 4b, duplicate a. (787 aa)
rac2Rac family small GTPase 2. (219 aa)
il34Si:ch211-239j19.3 protein. (213 aa)
grnaGranulin a. (1049 aa)
csf1rbColony-stimulating factor 1 receptor, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
MFAP4Wu:fj11g02. (246 aa)
itgamIntegrin, alpha M (complement component 3 receptor 3 subunit); Belongs to the integrin alpha chain family. (780 aa)
il1bInterleukin-1. (284 aa)
ccr2-2Chemokine (C-C motif) receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa)
ccr2Chemokine (C-C motif) receptor 2; Belongs to the G-protein coupled receptor 1 family. (354 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
csf1raMacrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the ac [...] (977 aa)
cxcr1Chemokine (C-X-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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