STRINGSTRING
nphs1 nphs1 actn3b actn3b actn3a actn3a mybpc1 mybpc1 vim vim krt4 krt4 tcap tcap itgb4 itgb4 tnni2a.4 tnni2a.4 acta1b acta1b slc35a1 slc35a1 nansa nansa uap1 uap1 serpine1 serpine1 krt8 krt8 pxnb pxnb col2a1a col2a1a tnnc2 tnnc2 ttn.2 ttn.2 vclb vclb vcla vcla myh7l myh7l hspa1b hspa1b actn2b actn2b tp53 tp53 nphs2 nphs2 myh9a myh9a col12a1a col12a1a tln1 tln1 tln2a tln2a cnn1b cnn1b foxo1a foxo1a gne gne nagk nagk pxna pxna actn4 actn4 tln2b tln2b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nphs1NPHS1 adhesion molecule, nephrin. (1287 aa)
actn3bActinin alpha 3b. (898 aa)
actn3aActinin alpha 3a. (896 aa)
mybpc1Myosin-binding protein C1. (1167 aa)
vimVimentin; Belongs to the intermediate filament family. (455 aa)
krt4Keratin 4; Belongs to the intermediate filament family. (497 aa)
tcapTitin-cap (telethonin). (179 aa)
itgb4Integrin beta. (1893 aa)
tnni2a.4Troponin I type 2a (skeletal, fast), tandem duplicate 4. (176 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
slc35a1Solute carrier family 35 member A1. (337 aa)
nansaN-acetylneuraminic acid synthase a. (359 aa)
uap1UDP-N-acetylglucosamine pyrophosphorylase 1. (504 aa)
serpine1Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (392 aa)
krt8Keratin, type II cytoskeletal 8; Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. (520 aa)
pxnbPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (525 aa)
col2a1aCollagen, type II, alpha 1a. (1491 aa)
tnnc2Fast skeletal muscle troponin C. (160 aa)
ttn.2Titin, tandem duplicate 2. (26265 aa)
vclbVinculin b. (987 aa)
vclaVinculin a. (1131 aa)
myh7lMyosin heavy chain 7-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1936 aa)
hspa1bSi:ch211-199o1.2; Belongs to the heat shock protein 70 family. (639 aa)
actn2bActinin, alpha 2b. (894 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. (369 aa)
nphs2NPHS2 stomatin family member, podocin. (406 aa)
myh9aMyosin, heavy chain 9a, non-muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1964 aa)
col12a1aCollagen, type XII, alpha 1a. (2975 aa)
tln1Talin 1. (2544 aa)
tln2aTalin 2a. (2543 aa)
cnn1bCalponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (296 aa)
foxo1aForkhead box protein O1-A; Transcriptional regulator of cell cycle arrest required for cellular stress responses (By similarity). May be involved in regulating cellular homeostasis in the eye. (652 aa)
gneGlucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase. (732 aa)
nagkN-acetylglucosamine kinase. (344 aa)
pxnaPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (532 aa)
actn4Actinin, alpha 4. (923 aa)
tln2bTalin 2b. (1537 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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