STRINGSTRING
myh6 myh6 ush1c ush1c cdh23 cdh23 slc45a2 slc45a2 tmc2b tmc2b acta1b acta1b myo6b myo6b lhfpl5b lhfpl5b myca myca TMC1 TMC1 lhfpl5a lhfpl5a ush1gb ush1gb tomt tomt myo7aa myo7aa pcdh15b pcdh15b cacna1da cacna1da pcdh15a pcdh15a cib2 cib2 otofb otofb cdh23-2 cdh23-2 otofa otofa tmie tmie
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
myh6Myosin, heavy chain 6, cardiac muscle, alpha; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1936 aa)
ush1cUsher syndrome 1C (Autosomal recessive, severe). (548 aa)
cdh23Cadherin-related 23. (2883 aa)
slc45a2Solute carrier family 45 member 2. (554 aa)
tmc2bTransmembrane channel-like protein 2-B; Belongs to the TMC family. (892 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
myo6bMyosin VIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1267 aa)
lhfpl5bLHFPL tetraspan subfamily member 5b. (221 aa)
mycaTranscriptional regulator Myc-A; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (409 aa)
TMC1Transmembrane channel-like protein 1; Probable ion channel required for the normal function of hair cells (By similarity). Component of the hair cell's mechanotransduction (MET) machinery ; Belongs to the TMC family. (990 aa)
lhfpl5aLHFPL tetraspan subfamily member 5a. (226 aa)
ush1gbUsher syndrome 1Gb (autosomal recessive). (488 aa)
tomtTransmembrane O-methyltransferase homolog; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones (By similarity). Required for auditory function. Component of the hair cell's mechanotransduction (MET) machinery. Involved in the assembly of the asymmetric tip-link MET complex. Required for transportation of TMC1 and TMC2 proteins into the mechanically sensitive stereocilia of the hair cells. The function in MET is independent of the enzymatic activity. (259 aa)
myo7aaMyosin VIIAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2190 aa)
pcdh15bProtocadherin-related 15b. (1907 aa)
cacna1daVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2082 aa)
pcdh15aProtocadherin-related 15a. (1796 aa)
cib2Calcium and integrin-binding family member 2. (187 aa)
otofbOtoferlin b. (1773 aa)
cdh23-2Cadherin-related 23. (436 aa)
otofaOtoferlin; Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion and in the control of neurotransmitter release at these output synapses. (1992 aa)
tmieTransmembrane inner ear. (231 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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