STRINGSTRING
il1b il1b faxdc2 faxdc2 il6r il6r eef1a1l1 eef1a1l1 stat4 stat4 stat1b stat1b mxc mxc eef1a2 eef1a2 irf10 irf10 fkbp5 fkbp5 tm7sf2 tm7sf2 fosab fosab il20ra il20ra c3a.3 c3a.3 nr3c1 nr3c1 egr1 egr1 socs1a socs1a h1-0 h1-0 tpi1b tpi1b cyp51 cyp51 mpeg1.2 mpeg1.2 sc5d sc5d irf1a irf1a h1-10 h1-10 mpeg1.1 mpeg1.1 npas4a npas4a msmo1 msmo1 eif5a2 eif5a2 irf8 irf8 pfkmb pfkmb lss lss irg1l irg1l klf9 klf9 per1a per1a socs3b socs3b insrb insrb si:dkey-37o8.1 si:dkey-37o8.1 sqlea sqlea eif5a eif5a egr4 egr4 eef1a1a eef1a1a smarca5 smarca5 ier2b ier2b c3a.2 c3a.2 grna grna eef1a1b eef1a1b zgc:153115 zgc:153115 irf9 irf9 nr3c2 nr3c2 ifi35 ifi35 il4r.2 il4r.2 il4r.1 il4r.1 homer1b homer1b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
il1bInterleukin-1. (284 aa)
faxdc2Fatty acid hydroxylase domain-containing 2; Belongs to the sterol desaturase family. (327 aa)
il6rInterleukin 6 receptor. (604 aa)
eef1a1l1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (462 aa)
stat4Signal transducer and activator of transcription. (741 aa)
stat1bSignal transducer and activator of transcription. (725 aa)
mxcInterferon-induced GTP-binding protein MxC; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (626 aa)
eef1a2Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa)
irf10Interferon regulatory factor 10. (392 aa)
fkbp5Peptidylprolyl isomerase. (453 aa)
tm7sf2Transmembrane 7 superfamily member 2. (421 aa)
fosabV-fos FBJ murine osteosarcoma viral oncogene homolog Ab. (349 aa)
il20raInterleukin 20 receptor, alpha. (492 aa)
c3a.3Complement component c3a, duplicate 3. (1651 aa)
nr3c1Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor). (746 aa)
egr1Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Mediates responses to ischemia and hypoxia; regulates the express [...] (511 aa)
socs1aSuppressor of cytokine-signaling 1a. (201 aa)
h1-0H1 histone family, member 0. (199 aa)
tpi1bTriosephosphate isomerase B; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (248 aa)
cyp51Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. (499 aa)
mpeg1.2Novel protein similar to H.sapiens MPEG1, macrophage expressed gene 1 (MPEG1, zgc:110354). (713 aa)
sc5dSterol-C5-desaturase; Belongs to the sterol desaturase family. (300 aa)
irf1aInterferon regulatory factor. (251 aa)
h1-10H1 histone family, member X. (192 aa)
mpeg1.1Macrophage-expressed 1, tandem duplicate 1. (718 aa)
npas4aNeuronal PAS domain-containing protein 4A; Transcription factor expressed in neurons of the brain that regulates the excitatory-inhibitory balance within neural circuits and is required for contextual memory in the hyppocampus. Plays a key role in the structural and functional plasticity of neurons. Acts as an early-response transcription factor in both excitatory and inhibitory neurons, where it induces distinct but overlapping sets of late- response genes in these two types of neurons, allowing the synapses that form on inhibitory and excitatory neurons to be modified by neuronal act [...] (933 aa)
msmo1Methylsterol monooxygenase 1; Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol; Belongs to the sterol desaturase family. (291 aa)
eif5a2Eukaryotic translation initiation factor 5A. (155 aa)
irf8Interferon regulatory factor 8. (423 aa)
pfkmbATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (776 aa)
lssTerpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (735 aa)
irg1lImmunoresponsive gene 1,-like. (498 aa)
klf9Kruppel-like factor 9. (216 aa)
per1aPeriod circadian clock 1a. (1352 aa)
socs3bSuppressor of cytokine-signaling 3b. (210 aa)
insrbTyrosine-protein kinase receptor. (1348 aa)
si:dkey-37o8.1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (483 aa)
sqleaSqualene epoxidase a. (557 aa)
eif5aEukaryotic translation initiation factor 5A. (155 aa)
egr4Early growth response 4. (352 aa)
eef1a1aElongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
smarca5SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a, member 5. (1035 aa)
ier2bImmediate early response 2b. (170 aa)
c3a.2Complement component c3a, duplicate 2. (1656 aa)
grnaGranulin a. (1049 aa)
eef1a1bElongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
zgc:153115Zgc:153115. (250 aa)
irf9Interferon regulatory factor 9. (428 aa)
nr3c2Nuclear receptor subfamily 3, group C, member 2. (970 aa)
ifi35Interferon-induced protein 35. (384 aa)
il4r.2Interleukin 4 receptor, tandem duplicate 1. (421 aa)
il4r.1Interleukin 4 receptor, tandem duplicate 1. (220 aa)
homer1bHomer scaffold protein 1b. (398 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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