STRINGSTRING
tnfsf10 tnfsf10 stat1b stat1b tnfb tnfb stat1a stat1a myd88 myd88 bcl2l1 bcl2l1 cycsb cycsb actb1 actb1 rel rel ikbke ikbke il10 il10 mtor mtor cd40 cd40 srsf1b srsf1b irak1 irak1 bcl2a bcl2a nfkb2 nfkb2 ifng1 ifng1 relb relb il12a il12a il6 il6 rela rela itgb1b itgb1b psip1a psip1a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tnfsf10Tumor necrosis factor (Ligand) superfamily, member 10 like 2; Belongs to the tumor necrosis factor family. (299 aa)
stat1bSignal transducer and activator of transcription. (725 aa)
tnfbTumor necrosis factor b (TNF superfamily, member 2). (242 aa)
stat1aSignal transducer and activator of transcription. (749 aa)
myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. (284 aa)
bcl2l1Bcl-XL-like protein 1. (238 aa)
cycsbCytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity). (104 aa)
actb1Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
relV-rel avian reticuloendotheliosis viral oncogene homolog. (596 aa)
ikbkeInhibitor of nuclear factor kappa B kinase subunit epsilon. (721 aa)
il10Interleukin-10. (180 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2563 aa)
cd40CD40 molecule, TNF receptor superfamily member 5. (286 aa)
srsf1bSerine/arginine-rich splicing factor 1B; May play a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Belongs to the splicing factor SR family. (245 aa)
irak1Interleukin-1 receptor-associated kinase 1. (686 aa)
bcl2aB-cell leukemia/lymphoma 2. (228 aa)
nfkb2Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100). (902 aa)
ifng1Interferon gamma 1. (179 aa)
relbV-rel avian reticuloendotheliosis viral oncogene homolog B. (582 aa)
il12aInterleukin 12a. (196 aa)
il6Interleukin 6 (interferon, beta 2). (231 aa)
relaV-rel avian reticuloendotheliosis viral oncogene homolog A. (455 aa)
itgb1bIntegrin beta; Belongs to the integrin beta chain family. (521 aa)
psip1aPC4 and SFRS1-interacting protein 1a. (413 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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