STRINGSTRING
cnbpb cnbpb casp3a casp3a ccng1 ccng1 arrb1 arrb1 tp53 tp53 rad50 rad50 nop58 nop58 cul3b cul3b nop10 nop10 zbtb14 zbtb14 csf1ra csf1ra topbp1 topbp1 nop56 nop56 dkc1 dkc1 atm atm arrb2b arrb2b pax3a pax3a poli poli pfkfb3 pfkfb3 cul3a cul3a arrb2a arrb2a ccnb1 ccnb1 cnbpa cnbpa myb myb fbl fbl casp3b casp3b plk1 plk1 ddx21 ddx21 nhp2 nhp2 nolc1 nolc1 kbtbd8 kbtbd8 dmrt2a dmrt2a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cnbpbCCHC-type zinc finger, nucleic acid-binding protein b. (161 aa)
casp3aCaspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (282 aa)
ccng1Cyclin G1; Belongs to the cyclin family. (299 aa)
arrb1Arrestin, beta 1. (418 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. (369 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
nop58NOP58 ribonucleoprotein homolog (yeast). (553 aa)
cul3bCullin 3b; Belongs to the cullin family. (766 aa)
nop10H/ACA ribonucleoprotein complex subunit 3; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). (64 aa)
zbtb14Zinc finger and BTB domain-containing 14. (442 aa)
csf1raMacrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Promotes reorganization of the ac [...] (977 aa)
topbp1DNA topoisomerase II-binding protein 1. (1526 aa)
nop56NOP56 ribonucleoprotein homolog. (548 aa)
dkc1Dyskeratosis congenita 1, dyskerin. (506 aa)
atmNon-specific serine/threonine protein kinase. (3091 aa)
arrb2bArrestin, beta 2b. (408 aa)
pax3aTranscription factor PAX3. (509 aa)
poliPolymerase (DNA directed) iota. (710 aa)
pfkfb36-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3. (536 aa)
cul3aCullin 3a; Belongs to the cullin family. (774 aa)
arrb2aArrestin, beta 2a. (406 aa)
ccnb1Cyclin B1; Belongs to the cyclin family. (397 aa)
cnbpaCCHC-type zinc finger, nucleic acid-binding protein a. (163 aa)
mybV-myb avian myeloblastosis viral oncogene homolog. (641 aa)
fblFibrillarin. (317 aa)
casp3bCaspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. (285 aa)
plk1Serine/threonine-protein kinase PLK. (595 aa)
ddx21DEAD (Asp-Glu-Ala-Asp) box helicase 21. (791 aa)
nhp2H/ACA ribonucleoprotein complex subunit 2-like protein; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). (150 aa)
nolc1Nucleolar and coiled-body phosphoprotein 1. (1001 aa)
kbtbd8Kelch repeat and BTB domain-containing protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification (By similarity). The BCR(KBTBD8) complex acts by mediating monoubiquitination of target proteins (By similarity). (601 aa)
dmrt2aDoublesex and mab-3-related transcription factor 2a. (507 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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