Your Input: | |||||
shha | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). (418 aa) | ||||
myf5 | Myogenic factor. (237 aa) | ||||
shhb | Tiggy-winkle hedgehog protein C-product; Intercellular signal essential for a variety of patterning events during development. Involved in dorso-ventral patterning of the brain and in early patterning of the developing eyes. (416 aa) | ||||
myod1 | Myoblast determination protein 1 homolog; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. (275 aa) | ||||
myog | Myogenin. (256 aa) | ||||
pax3a | Transcription factor PAX3. (509 aa) | ||||
myf6 | Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). (239 aa) | ||||
pax7a | Transcription factor PAX7C. (507 aa) | ||||
foxo1a | Forkhead box protein O1-A; Transcriptional regulator of cell cycle arrest required for cellular stress responses (By similarity). May be involved in regulating cellular homeostasis in the eye. (652 aa) | ||||
tp53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. (369 aa) |