Actin alpha 1, skeletal muscle b.

GATA-binding protein 1a.

Actin alpha 1, skeletal muscle b.

Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]

Actin alpha 1, skeletal muscle b.

Histone H3; Belongs to the histone H3 family.

Actin alpha 1, skeletal muscle b.

Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.

Actin alpha 1, skeletal muscle b.

Vascular endothelial growth factor receptor 2; Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels. Particularly involved in artery formation. Does not appear to be required for hematopoiesis.

Actin alpha 1, skeletal muscle b.

Vascular endothelial growth factor receptor kdr-like; Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels. Particularly involved in artery formation. Does not appear to be required for hematopoiesis.

Actin alpha 1, skeletal muscle b.

Mast/stem cell growth factor receptor kita; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine kitlg/scf and plays a role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, and in mast cell development, migration and function. Required for the migration of cells in the melanocyte lineage and the survival of embryonic melanocytes. Required for the differentiation of some, but not all, melanocytes. Not essential for hematopoiesis or primordial germ cell development.

Actin alpha 1, skeletal muscle b.

Kruppel-like factor 17.

Actin alpha 1, skeletal muscle b.

Kruppel-like factor 4.

Actin alpha 1, skeletal muscle b.

POU domain, class 5, transcription factor 1; Involved in early development of embryos, especially in the process of gastrulation. May play an important role in establishing and specifying rhombomeric segments. Seems to be required to maintain the cells in a highly undifferentiated state. In contrast to POU2, T-POU2 lacks DNA-binding activity because of its incomplete pou domain structure. Overexpression of POU2 does not have any effect on development, whereas overexpression of t-POU2 causes developmental retardation or arrest before gastrulation; Belongs to the POU transcription factor [...]

Actin alpha 1, skeletal muscle b.

Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression.

Actin alpha 1, skeletal muscle b.

Vinculin a.

Actin alpha 1, skeletal muscle b.

Vinculin b.

Actin alpha 1, skeletal muscle b.

Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Actin alpha 1, skeletal muscle b.

Si:dkey-108k21.24.

Actin alpha 1, skeletal muscle b.

Histone H3; Belongs to the histone H3 family.

5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

GATA-binding protein 1a.

Ash2-like, histone lysine methyltransferase complex subunit.

Histone-lysine N-methyltransferase, H3 lysine-79 specific.

Ash2-like, histone lysine methyltransferase complex subunit.

GATA-binding protein 1a.

Ash2-like, histone lysine methyltransferase complex subunit.

Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...]