STRINGSTRING
gpx1a gpx1a hsd17b8 hsd17b8 gpx1b gpx1b gpx8 gpx8 stat1a stat1a rfx3 rfx3 TXN TXN cftr cftr sod2 sod2 gpx3 gpx3 txn txn egf egf myb myb kera kera gpx4a gpx4a mybl2a mybl2a gpx7 gpx7 egfra egfra gpx9 gpx9 gmnc gmnc slc39a7 slc39a7 rps18 rps18 foxj1a foxj1a notch1a notch1a mcidas mcidas ulk4 ulk4 gpx4b gpx4b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gpx1aGlutathione peroxidase; Belongs to the glutathione peroxidase family. (191 aa)
hsd17b8FabG (Beta-ketoacyl-[acyl-carrier-protein] reductase, E. coli) like. (256 aa)
gpx1bGlutathione peroxidase; Belongs to the glutathione peroxidase family. (142 aa)
gpx8Probable glutathione peroxidase 8; Belongs to the glutathione peroxidase family. (210 aa)
stat1aSignal transducer and activator of transcription. (749 aa)
rfx3Transcription factor RFX3; Transcription factor required for ciliogenesis and islet cell differentiation during endocrine pancreas development; Belongs to the RFX family. (765 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (108 aa)
cftrCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1485 aa)
sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (224 aa)
gpx3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (222 aa)
txnThioredoxin; Belongs to the thioredoxin family. (107 aa)
egfEpidermal growth factor. (1114 aa)
mybV-myb avian myeloblastosis viral oncogene homolog. (641 aa)
keraKeratocan; May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. (348 aa)
gpx4aGlutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)
mybl2aV-myb avian myeloblastosis viral oncogene homolog-like 2a. (802 aa)
gpx7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)
egfraEpidermal growth factor receptor precursor. (625 aa)
gpx9Glutathione peroxidase; Belongs to the glutathione peroxidase family. (140 aa)
gmncGeminin coiled-coil domain-containing. (382 aa)
slc39a7Zinc transporter Slc39a7; Zinc transporter, that transports Zn(2+) from the endoplasmic reticulum/Golgi apparatus to the cytosol; Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily. (444 aa)
rps1840S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA (By similarity). Plays an essential role in early embryonic development. (152 aa)
foxj1aForkhead box protein J1-A; Key transcription factor required for motile ciliogenesis. Activates genes essential for motile cilia formation and function. Its activity is sufficient for ectopic development of cilia that resemble motile cilia. (458 aa)
notch1aNeurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] (2438 aa)
mcidasUncharacterized protein. (302 aa)
ulk4Unc-51-like kinase 4. (1285 aa)
gpx4bGlutathione peroxidase; Belongs to the glutathione peroxidase family. (170 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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