Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSDARP00000125042 | bmp2a | ENSDARP00000125042 | ENSDARP00000013686 | Patched 1. | Bone morphogenetic protein 2a. | 0.569 |
| ENSDARP00000125042 | bmp2b | ENSDARP00000125042 | ENSDARP00000107417 | Patched 1. | Bone morphogenetic protein 2b. | 0.529 |
| ENSDARP00000125042 | bmp4 | ENSDARP00000125042 | ENSDARP00000069635 | Patched 1. | Bone morphogenetic protein 4. | 0.626 |
| ENSDARP00000125042 | ctnnb1 | ENSDARP00000125042 | ENSDARP00000139205 | Patched 1. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.575 |
| ENSDARP00000125042 | gli1 | ENSDARP00000125042 | ENSDARP00000129932 | Patched 1. | GLI family zinc finger 1. | 0.961 |
| ENSDARP00000125042 | gli2a | ENSDARP00000125042 | ENSDARP00000010693 | Patched 1. | GLI family zinc finger 2a. | 0.959 |
| ENSDARP00000125042 | gli3 | ENSDARP00000125042 | ENSDARP00000058991 | Patched 1. | GLI family zinc finger 3. | 0.955 |
| ENSDARP00000125042 | ihhb | ENSDARP00000125042 | ENSDARP00000076199 | Patched 1. | Indian hedgehog B protein C-product; Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning and muscle pioneer differentiation. | 0.992 |
| ENSDARP00000125042 | notch1a | ENSDARP00000125042 | ENSDARP00000137942 | Patched 1. | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | 0.629 |
| ENSDARP00000125042 | shha | ENSDARP00000125042 | ENSDARP00000125090 | Patched 1. | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.999 |
| ENSDARP00000125042 | smo | ENSDARP00000125042 | ENSDARP00000013486 | Patched 1. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.996 |
| ENSDARP00000125042 | wnt5b | ENSDARP00000125042 | ENSDARP00000134193 | Patched 1. | Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. Required during embryogenesis for extension of the primary anterior-posterior axis. | 0.442 |
| bmp2a | ENSDARP00000125042 | ENSDARP00000013686 | ENSDARP00000125042 | Bone morphogenetic protein 2a. | Patched 1. | 0.569 |
| bmp2a | bmp7a | ENSDARP00000013686 | ENSDARP00000017352 | Bone morphogenetic protein 2a. | Bone morphogenetic protein 7a. | 0.682 |
| bmp2a | ctnnb1 | ENSDARP00000013686 | ENSDARP00000139205 | Bone morphogenetic protein 2a. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.616 |
| bmp2a | gata4 | ENSDARP00000013686 | ENSDARP00000135304 | Bone morphogenetic protein 2a. | GATA-binding protein 4. | 0.471 |
| bmp2a | ihhb | ENSDARP00000013686 | ENSDARP00000076199 | Bone morphogenetic protein 2a. | Indian hedgehog B protein C-product; Intercellular signal essential for a variety of patterning events during development. Signal produced by the notochord that induces somite patterning and muscle pioneer differentiation. | 0.530 |
| bmp2a | notch1a | ENSDARP00000013686 | ENSDARP00000137942 | Bone morphogenetic protein 2a. | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | 0.622 |
| bmp2a | ptch1 | ENSDARP00000013686 | ENSDARP00000025418 | Bone morphogenetic protein 2a. | Protein patched homolog 1. | 0.569 |
| bmp2a | ptch2 | ENSDARP00000013686 | ENSDARP00000071771 | Bone morphogenetic protein 2a. | Protein patched homolog 1; Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal (By similarity). Belongs to the patched family. | 0.579 |
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