STRINGSTRING
otog otog pcdh15b pcdh15b myo7ab myo7ab cdh1 cdh1 eps8a eps8a pcdh15a pcdh15a cib2 cib2 atp2b2 atp2b2 grna grna ush1c ush1c whrna whrna fscn2b fscn2b slc26a4 slc26a4 oc90 oc90 otogl otogl ush2a ush2a fscn2a fscn2a neurog1 neurog1 tectb tectb ENSDARP00000060652 ENSDARP00000060652 calb2a calb2a acta1b acta1b calb2b calb2b cdh23 cdh23 neurod1 neurod1 slc30a4 slc30a4 notch1a notch1a myo7aa myo7aa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
otogOtogelin. (3120 aa)
pcdh15bProtocadherin-related 15b. (1907 aa)
myo7abMyosin VIIAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2190 aa)
cdh1Cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. (877 aa)
eps8aEpidermal growth factor receptor pathway substrate 8a. (804 aa)
pcdh15aProtocadherin-related 15a. (1796 aa)
cib2Calcium and integrin-binding family member 2. (187 aa)
atp2b2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1253 aa)
grnaGranulin a. (1049 aa)
ush1cUsher syndrome 1C (Autosomal recessive, severe). (548 aa)
whrnaWhirlin a. (939 aa)
fscn2bFascin. (490 aa)
slc26a4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (760 aa)
oc90Otoconin 90. (939 aa)
otoglOtogelin-like. (2489 aa)
ush2aUsher syndrome 2A (autosomal recessive, mild). (5236 aa)
fscn2aFascin. (488 aa)
neurog1Neurogenin-1; Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon-Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specificati [...] (208 aa)
tectbZgc:101843 protein. (336 aa)
ENSDARP00000060652Si:ch211-57i17.5. (199 aa)
calb2aCalbindin 2, like. (271 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
calb2bCalbindin 2b. (269 aa)
cdh23Cadherin-related 23. (2883 aa)
neurod1Neurogenic differentiation factor 1; May act as a transcriptional activator. Differentiation factor required for neurogenesis. Acts as an upstream activator of isl1. (350 aa)
slc30a4Solute carrier family 30 (Zinc transporter), member 4. (345 aa)
notch1aNeurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] (2438 aa)
myo7aaMyosin VIIAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2190 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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