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aldh2.2 aldh2.2 aldh3a1 aldh3a1 cyp1a cyp1a E7FAM7_DANRE E7FAM7_DANRE cyp4t8 cyp4t8 zgc:101040 zgc:101040 tp53 tp53 dpp9 dpp9 cyp19a1a cyp19a1a aldh3a2b aldh3a2b ces2a ces2a esr1 esr1 gstm.1 gstm.1 cyp17a1 cyp17a1 aldh3a2a aldh3a2a gsta.2 gsta.2 aldh2.1 aldh2.1 cyp3c1 cyp3c1 aldh3b1 aldh3b1 aldh3b2 aldh3b2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aldh2.2Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family. (516 aa)
aldh3a1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (489 aa)
cyp1aCytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family. (519 aa)
E7FAM7_DANRESi:dkey-78a14.4; Belongs to the arylamine N-acetyltransferase family. (288 aa)
cyp4t8Cytochrome P450, family 4, subfamily T, polypeptide 8. (458 aa)
zgc:101040Zgc:101040; Belongs to the arylamine N-acetyltransferase family. (290 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. (369 aa)
dpp9Dipeptidyl-peptidase 9; Belongs to the peptidase S9B family. (861 aa)
cyp19a1aAromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (517 aa)
aldh3a2bAldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (490 aa)
ces2aCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (555 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues; Belongs to the nuclear hormone receptor family. NR3 subfamily. (569 aa)
gstm.1Glutathione S-transferase mu, tandem duplicate 1; Belongs to the GST superfamily. (219 aa)
cyp17a1Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (519 aa)
aldh3a2aAldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (488 aa)
gsta.2Glutathione S-transferase, alpha tandem duplicate 2; Belongs to the GST superfamily. (223 aa)
aldh2.1Aldehyde dehydrogenase 2 family member, tandem duplicate 1; Belongs to the aldehyde dehydrogenase family. (516 aa)
cyp3c1Cytochrome P450, family 3, subfamily c, polypeptide 1; Belongs to the cytochrome P450 family. (505 aa)
aldh3b1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (473 aa)
aldh3b2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (502 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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