(17 nodes) (2022) Could Alcohol Abuse and Dependence on Junk Foods Inducing Obesity andor Illicit Drug Use Represent Danger to Liver in Young People with Altered PsychologicalRelational Spheres or Emotional Problems? network (Danio rerio)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	aldh3a2b	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (490 aa)
	f2	Coagulation factor II (thrombin); Belongs to the peptidase S1 family. (635 aa)
	ins	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa)
	aldh3a2a	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (488 aa)
	ifnphi1	Interferon phi 1. (185 aa)
	stat5a	Signal transducer and activator of transcription. (785 aa)
	aldh3b1	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (473 aa)
	bdnf	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (270 aa)
	cnr1	Cannabinoid receptor; Involved in cannabinoid-induced CNS effects. Belongs to the G-protein coupled receptor 1 family. (475 aa)
	aldh3b2	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (502 aa)
	aldh3a1	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (489 aa)
	fgf21	Fibroblast growth factor 21; Belongs to the heparin-binding growth factors family. (194 aa)
	jak2a	Tyrosine-protein kinase. (1095 aa)
	nectin3b	Nectin-3-like protein; May play a role in cell-cell adhesion; Belongs to the nectin family. (574 aa)
	insb	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (159 aa)
	stat5b	Signal transducer and activator of transcription. (786 aa)
	jak2b	Tyrosine-protein kinase. (1126 aa)

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
aldh3a1	ins	ENSDARP00000143500	ENSDARP00000051221	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.449
aldh3a1	insb	ENSDARP00000143500	ENSDARP00000115146	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.439
aldh3a2a	ins	ENSDARP00000037108	ENSDARP00000051221	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.436
aldh3a2a	insb	ENSDARP00000037108	ENSDARP00000115146	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.434
aldh3a2b	ins	ENSDARP00000103212	ENSDARP00000051221	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.434
aldh3a2b	insb	ENSDARP00000103212	ENSDARP00000115146	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.430
aldh3b1	aldh3b2	ENSDARP00000002746	ENSDARP00000145611	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.903
aldh3b1	ins	ENSDARP00000002746	ENSDARP00000051221	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.436
aldh3b1	insb	ENSDARP00000002746	ENSDARP00000115146	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.437
aldh3b2	aldh3b1	ENSDARP00000145611	ENSDARP00000002746	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.903
aldh3b2	ins	ENSDARP00000145611	ENSDARP00000051221	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.436
aldh3b2	insb	ENSDARP00000145611	ENSDARP00000115146	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.434
bdnf	cnr1	ENSDARP00000010990	ENSDARP00000007647	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	Cannabinoid receptor; Involved in cannabinoid-induced CNS effects. Belongs to the G-protein coupled receptor 1 family.	0.513
bdnf	ins	ENSDARP00000010990	ENSDARP00000051221	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.789
bdnf	insb	ENSDARP00000010990	ENSDARP00000115146	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.789
cnr1	bdnf	ENSDARP00000007647	ENSDARP00000010990	Cannabinoid receptor; Involved in cannabinoid-induced CNS effects. Belongs to the G-protein coupled receptor 1 family.	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	0.513
fgf21	ins	ENSDARP00000140850	ENSDARP00000051221	Fibroblast growth factor 21; Belongs to the heparin-binding growth factors family.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.794
fgf21	insb	ENSDARP00000140850	ENSDARP00000115146	Fibroblast growth factor 21; Belongs to the heparin-binding growth factors family.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.793
ifnphi1	ins	ENSDARP00000033132	ENSDARP00000051221	Interferon phi 1.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.540
ifnphi1	insb	ENSDARP00000033132	ENSDARP00000115146	Interferon phi 1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.480

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