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| | vcla | Vinculin a. (1131 aa) |
| | lmod1b | Leiomodin 1b (smooth muscle). (671 aa) |
| | vclb | Vinculin b. (987 aa) |
| | hspa8 | Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...] (649 aa) |
| | yap1 | Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Required for expansion of the neural plate and neural plate border zone progenitor pools. Acts as a direct regulator of pax3 expression via interaction with tead1. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin netwo [...] (442 aa) |
| | tfam | Transcription factor A, mitochondrial. (277 aa) |
| | lmod3 | Leiomodin-3; Essential for the organization of sarcomeric thin filaments in skeletal muscle; Belongs to the tropomodulin family. (670 aa) |
| | srfa | Serum response factor a. (539 aa) |
| | actc1a | Actin, alpha, cardiac muscle 1a. (377 aa) |
| | mff | Mitochondrial fission factor homolog B; Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface (By similarity); Belongs to the Tango11 family. (230 aa) |
| | acta1b | Actin alpha 1, skeletal muscle b. (377 aa) |
| | bag3 | BCL2-associated athanogene 3. (480 aa) |
| | nr3c1 | Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor). (746 aa) |
| | flnca | Filamin C, gamma a (actin-binding protein 280). (2719 aa) |
| | dicer1 | Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...] (1865 aa) |
| | atp2a1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1005 aa) |
| | jph2 | Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (781 aa) |
| | cav3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (150 aa) |
| | nebl | Nebulette. (276 aa) |
| | tcap | Titin-cap (telethonin). (179 aa) |
| | smyd1a | SET and MYND domain-containing 1a. (465 aa) |
| | flncb | Filamin C, gamma b (actin-binding protein 280). (2773 aa) |
| | hsp90aa1.1 | Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] (725 aa) |
| | hnrnpua | Heterogeneous nuclear ribonucleoprotein Ua. (760 aa) |
| | hsp70.3 | Heat shock cognate 70-kd protein, tandem duplicate 3; Belongs to the heat shock protein 70 family. (643 aa) |
| | actn3b | Actinin alpha 3b. (898 aa) |
| | thraa | Thyroid hormone receptor alpha-A; High affinity receptor for triiodothyronine (By similarity). In the absence of thyroid hormone during late blastula stage development, acts as a transcriptional repressor. Whereas in the presence of thyroid hormone, can act as an activator of transcription. In addition, represses retinoic acid (RA)-signaling during blastula and gastrula stages of development; Belongs to the nuclear hormone receptor family. NR1 subfamily. (427 aa) |
| | gata4 | GATA-binding protein 4. (352 aa) |
| | rbm24a | RNA-binding protein 24; Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation. Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation. Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing. Involved in embry [...] (230 aa) |
| | gata6 | GATA-binding protein 6. (501 aa) |
| | csrp3 | Cysteine and glycine-rich protein 3 (cardiac LIM protein). (193 aa) |
| | lmnb2 | Lamin B2; Belongs to the intermediate filament family. (583 aa) |
| | pparg | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (116 aa) |
| | esrra | Estrogen-related receptor alpha. (436 aa) |
| | esrrb | Estrogen-related receptor beta. (437 aa) |
| | zgc:110130 | Mitochondrial fission factor homolog A; Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface (By similarity); Belongs to the Tango11 family. (286 aa) |
| | Flnb | Uncharacterized protein. (157 aa) |
| | thrb | Thyroid hormone receptor beta; Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for the thyroid gland hormone triiodothyronine (T3). Transactivating activity is ligand-dependent, and is repressed in the absence of T3. (508 aa) |
| | tln2b | Talin 2b. (1537 aa) |
| | lmna | Lamin A; Belongs to the intermediate filament family. (675 aa) |
| | smyd1b | SET and MYND domain-containing 1b. (486 aa) |
| | lsr | Lipolysis-stimulated lipoprotein receptor. (599 aa) |
| | tln1 | Talin 1. (2544 aa) |
| | tln2a | Talin 2a. (2543 aa) |
| | neb | Nebulin. (6177 aa) |
| | lmod2b | Leiomodin 2 (cardiac) b. (604 aa) |
| | stk38b | Serine/threonine kinase 38b; Belongs to the protein kinase superfamily. (468 aa) |
| | actn2b | Actinin, alpha 2b. (894 aa) |
| | flnb | Filamin B, beta (actin-binding protein 278). (2233 aa) |
| | flna | Filamin A, alpha (actin-binding protein 280). (2553 aa) |
| | hopx | Homeodomain-only protein; Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. May act via an interaction with SRF, leading to modulate the expression of SRF- dependent cardiac-specific genes and cardiac development. May act as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assist in chaperone-mediated protein refolding (By similarity). (77 aa) |
| | hnrnpub | Heterogeneous nuclear ribonucleoprotein Ub. (796 aa) |
| | sun1 | Sad1 and UNC84 domain-containing 1. (997 aa) |
| | hsp70.1 | Heat shock cognate 70-kd protein, tandem duplicate 1; Belongs to the heat shock protein 70 family. (643 aa) |
| | ttn.1 | Titin, tandem duplicate 1. (29152 aa) |
| | nrap | Nebulin-related-anchoring protein. (1861 aa) |
