STRINGSTRING
twf2 twf2 acta1b acta1b gnai3 gnai3 cdh23 cdh23 gpsm2 gpsm2 myo7aa myo7aa capzb capzb eps8a eps8a cib2 cib2 eps8l2 eps8l2 myo15aa myo15aa loxhd1a loxhd1a cdh23-2 cdh23-2 whrnb whrnb cib3 cib3 whrna whrna TMC1 TMC1 slc17a8 slc17a8 lhfpl5b lhfpl5b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
twf2Twinfilin-2; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin (By similarity). (347 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
gnai3Guanine nucleotide-binding protein (G protein), alpha-inhibiting activity polypeptide 3. (354 aa)
cdh23Cadherin-related 23. (2883 aa)
gpsm2G protein-signaling modulator 2. (649 aa)
myo7aaMyosin VIIAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2190 aa)
capzbF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (273 aa)
eps8aEpidermal growth factor receptor pathway substrate 8a. (804 aa)
cib2Calcium and integrin-binding family member 2. (187 aa)
eps8l2EPS8-like 2. (670 aa)
myo15aaMyosin XVAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (4115 aa)
loxhd1aLipoxygenase homology domains 1a. (2122 aa)
cdh23-2Cadherin-related 23. (436 aa)
whrnbWhirlin b. (946 aa)
cib3Calcium and integrin-binding family member 3. (180 aa)
whrnaWhirlin a. (939 aa)
TMC1Transmembrane channel-like protein 1; Probable ion channel required for the normal function of hair cells (By similarity). Component of the hair cell's mechanotransduction (MET) machinery ; Belongs to the TMC family. (990 aa)
slc17a8Vesicular glutamate transporter 3; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. (590 aa)
lhfpl5bLHFPL tetraspan subfamily member 5b. (221 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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