Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| apoeb | casp3a | ENSDARP00000058964 | ENSDARP00000006831 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | 0.486 |
| apoeb | casp3b | ENSDARP00000058964 | ENSDARP00000071815 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. | 0.483 |
| apoeb | cd36 | ENSDARP00000058964 | ENSDARP00000050752 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | CD36 molecule (thrombospondin receptor); Belongs to the CD36 family. | 0.719 |
| apoeb | cybb | ENSDARP00000058964 | ENSDARP00000073592 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | Cytochrome b-245, beta polypeptide (chronic granulomatous disease). | 0.407 |
| apoeb | hmox1a | ENSDARP00000058964 | ENSDARP00000038993 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. | 0.441 |
| apoeb | lectin | ENSDARP00000058964 | ENSDARP00000102618 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | Lectin. | 0.402 |
| apoeb | nfe2l2a | ENSDARP00000058964 | ENSDARP00000062853 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | Nuclear factor (Erythroid-derived 2)-like 2. | 0.405 |
| apoeb | notch1a | ENSDARP00000058964 | ENSDARP00000137942 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | 0.432 |
| apoeb | stat3 | ENSDARP00000058964 | ENSDARP00000095292 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | Signal transducer and activator of transcription. | 0.464 |
| apoeb | vcam1b | ENSDARP00000058964 | ENSDARP00000144690 | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | Vascular cell adhesion molecule 1b. | 0.754 |
| bach2b | hmox1a | ENSDARP00000116013 | ENSDARP00000038993 | BTB and CNC homology 1, basic leucine zipper transcription factor 2b. | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. | 0.412 |
| bach2b | nfe2l3 | ENSDARP00000116013 | ENSDARP00000150367 | BTB and CNC homology 1, basic leucine zipper transcription factor 2b. | Nuclear factor, erythroid 2-like 3. | 0.406 |
| casp3a | apoeb | ENSDARP00000006831 | ENSDARP00000058964 | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. | 0.486 |
| casp3a | casp3b | ENSDARP00000006831 | ENSDARP00000071815 | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | Caspase 3, apoptosis-related cysteine peptidase b; Belongs to the peptidase C14A family. | 0.903 |
| casp3a | cybb | ENSDARP00000006831 | ENSDARP00000073592 | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | Cytochrome b-245, beta polypeptide (chronic granulomatous disease). | 0.404 |
| casp3a | gsk3ba | ENSDARP00000006831 | ENSDARP00000027785 | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. | 0.616 |
| casp3a | hmox1a | ENSDARP00000006831 | ENSDARP00000038993 | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. | 0.703 |
| casp3a | keap1a | ENSDARP00000006831 | ENSDARP00000045762 | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | Kelch-like ECH-associated protein 1A; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | 0.458 |
| casp3a | lectin | ENSDARP00000006831 | ENSDARP00000102618 | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | Lectin. | 0.454 |
| casp3a | loxa | ENSDARP00000006831 | ENSDARP00000110708 | Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. | Lysyl oxidase a. | 0.473 |
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