STRINGSTRING
asip1 asip1 mc5ra mc5ra agrp agrp pcsk1 pcsk1 mc4r mc4r pomca pomca mc5rb mc5rb mc2r mc2r mc3r mc3r pomcb pomcb ddx4 ddx4 piwil1 piwil1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
asip1Agouti-signaling protein 1. (125 aa)
mc5raMelanocortin 5a receptor. (328 aa)
agrpAgouti-related neuropeptide. (126 aa)
pcsk1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (755 aa)
mc4rMelanocortin receptor 4; Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). (326 aa)
pomcaPro-opiomelanocortin protein. (222 aa)
mc5rbMelanocortin 5b receptor. (328 aa)
mc2rMelanocortin 2 receptor. (304 aa)
mc3rMelanocortin 3 receptor. (327 aa)
pomcbProopiomelanocortin b. (215 aa)
ddx4DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; Belongs to the DEAD box helicase family. (716 aa)
piwil1Piwi-like protein 1; Plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer- independent mechanism and are primarily derived from transposons and other [...] (858 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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