STRINGSTRING
col18a1a col18a1a actn3a actn3a cdh11 cdh11 pdlim3a pdlim3a degs1 degs1 gsk3ab gsk3ab mapk8b mapk8b pdlim3b pdlim3b mdkb mdkb frzb frzb dab2 dab2 tpm4a tpm4a myl7 myl7 myh11a myh11a mylka mylka acox1 acox1 slc27a2a slc27a2a sfrp5 sfrp5 ptk2bb ptk2bb lygl1 lygl1 sost sost agpat5 agpat5 dvl3a dvl3a dkk3b dkk3b itga6a itga6a agpat3 agpat3 lpcat3 lpcat3 ptgs1 ptgs1 slc27a6 slc27a6 acsbg2 acsbg2 gpat3 gpat3 sgms1 sgms1 myh9a myh9a myh10 myh10 tpm3 tpm3 sphk2 sphk2 lama2 lama2 tpm2 tpm2 chrm2a chrm2a sorbs1 sorbs1 ifitm5 ifitm5 postnb postnb dvl3 dvl3 tpma tpma tpm1 tpm1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
col18a1aCollagen type XVIII alpha 1 chain a. (1383 aa)
actn3aActinin alpha 3a. (896 aa)
cdh11Cadherin 11, type 2, OB-cadherin (osteoblast); Cadherins are calcium-dependent cell adhesion proteins. (800 aa)
pdlim3aPDZ and LIM domain 3a. (307 aa)
degs1Delta(4)-desaturase, sphingolipid 1. (323 aa)
gsk3abGlycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
mapk8bMitogen-activated protein kinase 8; Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. May play a role in the regulation of the circadian clock. (384 aa)
pdlim3bPDZ and LIM domain 3b. (315 aa)
mdkbMidkine-related growth factor Mdk2. (147 aa)
frzbFrizzled-related protein. (315 aa)
dab2DAB adaptor protein 2. (589 aa)
tpm4aTropomyosin 4a; Belongs to the tropomyosin family. (284 aa)
myl7Myosin, light polypeptide 7, regulatory. (172 aa)
myh11aMyosin, heavy polypeptide 11, smooth muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1974 aa)
mylkaMyosin, light chain kinase a. (899 aa)
acox1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (660 aa)
slc27a2aSolute carrier family 27 member 2a. (614 aa)
sfrp5Secreted frizzled-related protein 5. (310 aa)
ptk2bbProtein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1004 aa)
lygl1Lysozyme g. (196 aa)
sostSclerostin. (210 aa)
agpat51-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon). (365 aa)
dvl3aDishevelled segment polarity protein 3a. (676 aa)
dkk3bDickkopf WNT-signaling pathway inhibitor 3b. (283 aa)
itga6aIntegrin, alpha 6a; Belongs to the integrin alpha chain family. (1092 aa)
agpat31-acylglycerol-3-phosphate O-acyltransferase 3. (377 aa)
lpcat3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (465 aa)
ptgs1Prostaglandin-endoperoxide synthase 1. (597 aa)
slc27a6Solute carrier family 27 member 6. (618 aa)
acsbg2Acyl-CoA synthetase bubblegum family member 2. (794 aa)
gpat3Glycerol-3-phosphate acyltransferase 3; Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3- phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone (By similarity). Also converts LPA into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). (450 aa)
sgms1Sphingomyelin synthase 1. (404 aa)
myh9aMyosin, heavy chain 9a, non-muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1964 aa)
myh10Myosin, heavy chain 10, non-muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1992 aa)
tpm3Tropomyosin 3; Belongs to the tropomyosin family. (284 aa)
sphk2Sphingosine kinase 2. (869 aa)
lama2Laminin, alpha 2. (845 aa)
tpm2Tropomyosin 2 (beta); Belongs to the tropomyosin family. (284 aa)
chrm2aMuscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (495 aa)
sorbs1Sorbin and SH3 domain-containing 1. (766 aa)
ifitm5Interferon-induced transmembrane protein 5. (142 aa)
postnbPeriostin, osteoblast-specific factor b. (782 aa)
dvl3Dishevelled segment polarity protein 3b. (706 aa)
tpmaTropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments; Belongs to the tropomyosin family. (284 aa)
tpm1Tropomyosin 1 (alpha); Belongs to the tropomyosin family. (284 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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