STRINGSTRING
cse1l cse1l svild svild svila svila tnnt1 tnnt1 tpma tpma pdlim7 pdlim7 smyhc2-2 smyhc2-2 svilc svilc tpm3 tpm3 neb neb svilb svilb nubp2 nubp2 nrap nrap myot myot myh7 myh7 ilk ilk dpysl3 dpysl3 acta1b acta1b tnnt2c tnnt2c ifnphi1 ifnphi1 tcap tcap actn3b actn3b cfl2 cfl2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cse1lExportin-2; Export receptor for importin alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm (By similarity). Negatively regulates fluid secretion and plays a role in fluid homeostasis by downregulating cftr activity. (971 aa)
svildSupervillin d. (1468 aa)
svilaSupervillin a. (1763 aa)
tnnt1Troponin T type 1 (skeletal, slow). (342 aa)
tpmaTropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments; Belongs to the tropomyosin family. (284 aa)
pdlim7PDZ and LIM domain protein 7; May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues (By similarity). (419 aa)
smyhc2-2Slow myosin heavy chain 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (184 aa)
svilcSupervillin c. (1531 aa)
tpm3Tropomyosin 3; Belongs to the tropomyosin family. (284 aa)
nebNebulin. (6177 aa)
svilbSupervillin b. (179 aa)
nubp2Cytosolic Fe-S cluster assembly factor nubp2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The nubp1-nubp2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (269 aa)
nrapNebulin-related-anchoring protein. (1861 aa)
myotMyotilin. (561 aa)
myh7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
ilkIntegrin-linked kinase. (452 aa)
dpysl3Dihydropyrimidinase-related protein 3; Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. (567 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
tnnt2cTroponin T1, skeletal, slow. (290 aa)
ifnphi1Interferon phi 1. (185 aa)
tcapTitin-cap (telethonin). (179 aa)
actn3bActinin alpha 3b. (898 aa)
cfl2Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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